氧饱和度指数：先天性膈疝中氧合指数的辅助指标。
Oxygen saturation index: an adjunct for oxygenation index in congenital diaphragmatic hernia.
作者信息
Hari Gopal Srirupa, Martinek Kelly F, Holmes Amanda, Hagan Joseph L, Fernandes Caraciolo J
机构信息
Division of Neonatal-Perinatal Medicine, Baylor College of Medicine/Texas Children's Hospital, Houston, TX, USA.
出版信息
J Perinatol. 2024 Mar;44(3):354-359. doi: 10.1038/s41372-023-01845-8. Epub 2023 Dec 9.
OBJECTIVE
Our objective was to investigate the correlation of Oxygen Saturation Index (OSI) with Oxygenation Index (OI) and determine OSImax values that could predict need for ECMO and death in Congenital Diaphragmatic Hernia (CDH).
STUDY DESIGN
This is a retrospective cohort study of infants with CDH admitted to a tertiary level VI NICU. Pearson's correlation coefficient and simple linear regression analysis were used to investigate the OSI: OI correlation, and logistic regression analysis to investigate OSImax values that predicted need for ECMO and death.
RESULTS
Among the 180 infants, OSImax value of >13 at 6 h of life (HOL) best predicted need for ECMO and death. There was a strong correlation between OSI: OI paired values (r = 0.876, p < 0.001). The linear regression equation was OI = -2.4 + 2.4(OSI).
CONCLUSION
OSI could be used as a valuable adjunct to OI in the clinical management of newborn infants with CDH.
目的
我们的目的是研究氧饱和度指数（OSI）与氧合指数（OI）之间的相关性，并确定可预测先天性膈疝（CDH）患儿体外膜肺氧合（ECMO）需求和死亡情况的最大OSI值。
研究设计
这是一项对入住三级VI级新生儿重症监护病房（NICU）的CDH患儿进行的回顾性队列研究。采用Pearson相关系数和简单线性回归分析来研究OSI与OI的相关性，并采用逻辑回归分析来研究预测ECMO需求和死亡情况的最大OSI值。
结果
在180例婴儿中，出生后6小时（HOL）时最大OSI值>13最能预测ECMO需求和死亡情况。OSI与OI配对值之间存在强相关性（r = 0.876，p < 0.001）。线性回归方程为OI = -2.4 + 2.4（OSI）。
结论
在CDH新生儿的临床管理中，OSI可作为OI的重要辅助指标。
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