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浅析菊苣酸具有广阔的治疗潜力。

An Insight into the Promising Therapeutic Potential of Chicoric Acid.

机构信息

Institute of Pharmaceutical Research, GLA University, Mathura, Uttar Pradesh, India.

出版信息

Curr Pharm Biotechnol. 2024;25(13):1708-1718. doi: 10.2174/0113892010280616231127075921.

Abstract

The pharmacological treatments that are now recommended for the therapy of chronic illnesses are examined in a great number of studies to determine whether or not they are both safe and effective. Therefore, it is important to investigate various alternative therapeutic assistance, such as natural remedies derived from medicinal plants. In this context, chicoric acid, classified as a hydroxycinnamic acid, has been documented to exhibit a range of health advantages. These include antiviral, antioxidant, anti-inflammatory, obesity-preventing, and neuroprotective effects. Due to its considerable pharmacological properties, chicoric acid has found extensive applications in food, pharmaceuticals, animal husbandry, and various other commercial sectors. This article provides a comprehensive overview of and in vivo investigations on chicoric acid, highlighting its beneficial effects and therapeutic activity when used as a preventative and management aid for public health conditions, including diabetes, cardiovascular disease, and hepatic illnesses like non-alcoholic steatohepatitis. Moreover, further investigation of this compound can lead to its development as a potential phytopharmaceutical candidate.

摘要

大量研究考察了现推荐用于慢性病治疗的药理学治疗方法,以确定它们是否安全有效。因此,研究各种替代治疗辅助手段很重要,例如来自药用植物的天然疗法。在这种情况下,菊苣酸被归类为羟基肉桂酸,已被证明具有多种健康益处。这些益处包括抗病毒、抗氧化、抗炎、预防肥胖和神经保护作用。由于其相当多的药理学特性,菊苣酸已在食品、制药、畜牧业和其他各种商业领域得到广泛应用。本文全面概述了菊苣酸的 和体内研究,强调了其作为公共卫生状况(包括糖尿病、心血管疾病和非酒精性脂肪性肝炎等肝脏疾病)的预防和管理辅助手段的有益作用和治疗活性。此外,对这种化合物的进一步研究可能导致其开发成为一种潜在的植物药候选物。

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