Zheng Haige, Wang Fang, Li Yang, Li Zhicheng, Zhang Xiaochun, Yin Xuntao
Department of Radiology, Guangzhou Women and Children's Medical Center Guangdong Provincial Clinical Research Center for Child Health Guangzhou China.
Lianying Intelligent Medical Technology (Chengdu) Co., Ltd. Chengdu China.
Cancer Innov. 2023 Feb 19;2(4):302-311. doi: 10.1002/cai2.44. eCollection 2023 Aug.
Radiomics is widely used in adult tumors but has been rarely applied to the field of pediatrics. Promoting the application of radiomics in pediatric diseases, especially in the early diagnosis and stratified treatment of tumors, is of great value to the realization of the WHO 2030 "Global Initiative for Childhood Cancer." This paper discusses the general characteristics of radiomics, the particularity of its application to pediatric diseases, and the current status and prospects of pediatric radiomics. Radiomics is a data-driven science, and the combination of medicine and engineering plays a decisive role in improving data quality, data diversity, and sample size. Compared with adult radiomics, pediatric radiomics is significantly different in data type, disease spectrum, disease staging, and progression. Some progress has been made in the identification, classification, stratification, survival prediction, and prognosis of tumor diseases. In the future, big data applications from multiple centers and cross-talent training should be strengthened to improve the benefits for clinical workers and children.
放射组学在成人肿瘤中广泛应用，但在儿科领域应用较少。推动放射组学在儿科疾病中的应用，尤其是在肿瘤的早期诊断和分层治疗中，对于实现世界卫生组织2030年“全球儿童癌症倡议”具有重要价值。本文讨论了放射组学的一般特征、其在儿科疾病中应用的特殊性以及儿科放射组学的现状与前景。放射组学是一门数据驱动的科学，医学与工程学的结合在提高数据质量、数据多样性和样本量方面起着决定性作用。与成人放射组学相比，儿科放射组学在数据类型、疾病谱、疾病分期和进展方面存在显著差异。在肿瘤疾病的识别、分类、分层、生存预测和预后方面已取得一些进展。未来，应加强多中心大数据应用和跨专业人才培养，以提高对临床工作者和儿童的益处。
