一例罕见的前列腺癌肌肉转移病例报告。

A rare case report of muscular metastasis of prostate cancer.

作者信息

Ayati Mohsen, Shiraghaee Mohsen, Amini Erfan, Rakhshani Nasser, Sharifi Laleh

机构信息

Uro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Department of Pathology, Gastrointestinal and Liver Diseases Research Centre, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Urol Case Rep. 2023 Nov 27;51:102619. doi: 10.1016/j.eucr.2023.102619. eCollection 2023 Nov.

DOI:10.1016/j.eucr.2023.102619

PMID:38093734

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10715993/

Abstract

Skeletal muscle metastasis of prostate cancer is a very rare phenomenon that has only been described in limited case reports. In this study, we present a case of neuroendocrine prostate cancer with muscle metastasis, a histological subtype associated with a grim prognosis. This case illustrates the potential efficacy of urgent surgical resection of the metastatic muscle mass, followed by adjuvant radiation therapy, as a suitable management strategy for this condition. However, a comprehensive understanding of the biological characteristics of neuroendocrine prostate cancer is imperative in our fight against this lethal form of the disease and in the prevention of metastatic spread.

摘要

前列腺癌的骨骼肌转移是一种非常罕见的现象，仅在有限的病例报告中有所描述。在本研究中，我们报告了一例伴有肌肉转移的神经内分泌前列腺癌病例，该组织学亚型预后较差。该病例说明了紧急手术切除转移的肌肉肿块，随后进行辅助放射治疗，作为这种病症的合适治疗策略的潜在疗效。然而，全面了解神经内分泌前列腺癌的生物学特性对于我们对抗这种致命疾病形式及预防转移扩散至关重要。