Department of Physical Education and Sport Sciences, National Taiwan Normal University, Taipei, Taiwan.
Psychophysiology. 2024 Feb;61(2):e14489. doi: 10.1111/psyp.14489. Epub 2023 Dec 14.
According to the locus coeruleus-norepinephrine (LC-NE) theory, activity of the LC, the major releaser of NE in the brain, regulates inhibitory control. As there is reciprocal communication between circulating epinephrine and the LC, plasma epinephrine is used as the index of LC-NE activity. The aim of this crossover randomized controlled trial is to expand on previous findings by investigating the effects of free-weight, multiple-joint, and structural barbell resistance exercises. Previous studies have had some methodological limitations, such as failure to report the process of randomization, absence of resistance exercise familiarization before the maximal strength testing, and lack of protocol publication. To address these issues, this study incorporates resistance exercise familiarization, transparent reporting of randomization, and submission as a registered report. The results suggest that a single session of resistance exercise (barbell squat, press, and deadlift) with an intensity of 65%-78% 1RM for five repetitions (70%-90% relative intensity) and three sets with 3-min rest intervals improved Stroop congruent reaction time (RT) only (t(27) = -2.663, mean reduction = -15 ms, p = .013, 95% CI [-26, -3]). No significant enhancements were observed in Stroop incongruent RT, inhibitory control as indexed by Stroop effect, or inhibitory control as indexed by the RT difference between the Stroop task and the simple reaction task. Moreover, the alterations in plasma epinephrine levels did not significantly associate with changes in any measure of cognitive performance.
根据蓝斑-去甲肾上腺素（LC-NE）理论，LC 的活动——大脑中去甲肾上腺素的主要释放者——调节抑制控制。由于循环肾上腺素与 LC 之间存在相互交流，因此血浆肾上腺素被用作 LC-NE 活动的指标。本交叉随机对照试验的目的是通过研究自由重量、多关节和结构性杠铃阻力运动的效果来扩展以前的发现。以前的研究存在一些方法学上的局限性，例如未能报告随机化过程，在最大力量测试之前没有进行阻力运动适应，以及缺乏方案发布。为了解决这些问题，本研究纳入了阻力运动适应，随机化过程的透明报告，并作为注册报告提交。结果表明，单次阻力运动（杠铃深蹲、卧推和硬拉），强度为 65%-78% 1RM 重复 5 次（70%-90%相对强度），3 组，每组间隔 3 分钟，仅改善 Stroop 一致反应时间（RT）（t(27)=-2.663，平均减少 15 毫秒，p=0.013，95%置信区间 [-26，-3]）。Stroop 不一致 RT、Stroop 效应指标的抑制控制或 Stroop 任务与简单反应任务 RT 差异指标的抑制控制均未观察到显著增强。此外，血浆肾上腺素水平的变化与认知表现的任何测量值的变化均无显著相关性。
