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预测视网膜前膜眼术后视力功能的相关因素。

Predictive factors for postoperative visual function in eyes with epiretinal membrane.

机构信息

Department of Ophthalmology and Micro-Technology, Yokohama City University, 4-57 Urafune, Minami-ku, Yokohama, Kanagawa, 232-0024, Japan.

Department of Ophthalmology, Addenbrookes Hospital, Cambridge, UK.

出版信息

Sci Rep. 2023 Dec 14;13(1):22198. doi: 10.1038/s41598-023-49689-8.

Abstract

Our current study aimed to investigate the association of preoperative OCT parameters with visual function after vitrectomy surgery in eyes with epiretinal membrane (ERM). This study enrolled 33 eyes with ERM that underwent vitrectomy surgery. In addition to visual acuity (VA), metamorphopsia was measured pre- and postoperatively for each eye. Using the preoperative horizontal and vertical OCT images, SUKIMA (the gap area between the ERM and retinal surface) was measured respectively and the average of horizontal SUKIMA and vertical SUKIMA was used for the analysis. The associations of baseline parameters (age, axial length, preoperative central retinal thickness [CRT], inner nuclear layer [INL] thickness, ectopic inner foveal layer [EIFL] and SUKIMA) with postoperative VA, the change in VA, postoperative metamorphopsia and the improvement in metamorphopsia were investigated using multivariate regression analysis followed by the model selection. The result suggested that age and INL thickness were related to the postoperative VA, whereas age and preoperative CRT were significantly associated with the change in VA. In contrast, only SUKIMA was correlated with the postoperative metamorphopsia, whilst age, EIFL and SUKIMA were associated with the improvement in metamorphopsia. Measuring SUKIMA might be useful for predicting postoperative metamorphopsia and the improvement in metamorphopsia in ERM eyes.

摘要

我们目前的研究旨在探讨眼内细胞外基质(ERM)手术后 OCT 参数与视力功能的关系。本研究纳入了 33 只接受玻璃体切除术的 ERM 眼。除了视力(VA)外,我们还对每只眼进行了术前和术后的视物变形的测量。使用术前水平和垂直 OCT 图像,分别测量 SUKIMA(ERM 和视网膜表面之间的间隙面积),并分析水平 SUKIMA 和垂直 SUKIMA 的平均值。采用多元回归分析和模型选择,探讨基线参数(年龄、眼轴长度、术前中央视网膜厚度[CRT]、内核层[INL]厚度、异位中心凹内层[EIFL]和 SUKIMA)与术后 VA、VA 变化、术后视物变形和视物变形改善的相关性。结果表明,年龄和 INL 厚度与术后 VA 相关,而年龄和术前 CRT 与 VA 变化显著相关。相比之下,只有 SUKIMA 与术后视物变形相关,而年龄、EIFL 和 SUKIMA 与视物变形改善相关。测量 SUKIMA 可能有助于预测 ERM 眼术后视物变形和视物变形改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15e8/10721818/613b02b2b943/41598_2023_49689_Fig1_HTML.jpg

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