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基于优化深度学习方法的耳部疾病自动图像诊断研究进展。

Insight into Automatic Image Diagnosis of Ear Conditions Based on Optimized Deep Learning Approach.

机构信息

Systems and Biomedical Engineering Department, Higher Institute of Engineering in Shorouk Academy, Al Shorouk City, Cairo, Egypt.

Scientific Research Group in Egypt (SRGE), Cairo, Egypt.

出版信息

Ann Biomed Eng. 2024 Apr;52(4):865-876. doi: 10.1007/s10439-023-03422-8. Epub 2023 Dec 14.

DOI:10.1007/s10439-023-03422-8
PMID:38097895
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10940396/
Abstract

Examining otoscopic images for ear diseases is necessary when the clinical diagnosis of ear diseases extracted from the knowledge of otolaryngologists is limited. Improved diagnosis approaches based on otoscopic image processing are urgently needed. Recently, convolutional neural networks (CNNs) have been carried out for medical diagnosis to obtain higher accuracy than standard machine learning algorithms and specialists' expertise. Therefore, the proposed approach involves using the Bayesian hyperparameter optimization with the CNN architecture for automatic diagnosis of ear imagery database including four classes: normal, myringosclerosis, earwax plug, and chronic otitis media (COM). The suggested approach was trained using 616 otoscopic images, and the performance of this approach was assessed using 264 testing images. In this paper, the performance of ear disease classification was compared in terms of accuracy, sensitivity, specificity, and positive predictive value (PPV). The results produced a classification accuracy of 98.10%, a sensitivity of 98.11%, a specificity of 99.36%, and a PPV of 98.10%. Finally, the suggested approach demonstrates how to locate optimal CNN hyperparameters for accurate diagnosis of ear diseases while taking time into account. As a result, the usefulness and dependability of the suggested approach will lead to the establishment of an automated tool for better categorization and prediction of different ear diseases.

摘要

当从耳鼻喉科医生那里获得的有关耳部疾病的临床诊断受到限制时,检查耳镜图像对于诊断耳部疾病是必要的。基于耳镜图像处理的改进诊断方法是迫切需要的。最近,卷积神经网络(CNN)已经被用于医学诊断,以获得比标准机器学习算法和专家知识更高的准确性。因此,所提出的方法涉及使用贝叶斯超参数优化与 CNN 架构,对包括正常、鼓膜硬化症、耳垢栓塞和慢性中耳炎(COM)在内的四个类别的耳镜图像数据库进行自动诊断。该方法使用 616 个耳镜图像进行训练,并使用 264 个测试图像来评估该方法的性能。在本文中,基于准确性、敏感性、特异性和阳性预测值(PPV)来比较耳部疾病分类的性能。结果产生了 98.10%的分类准确性、98.11%的敏感性、99.36%的特异性和 98.10%的阳性预测值。最后,该方法展示了如何在考虑时间的情况下找到准确诊断耳部疾病的最佳 CNN 超参数。因此,所提出方法的有用性和可靠性将导致建立一个自动工具,用于更好地对不同耳部疾病进行分类和预测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c3/10940396/0fa18638ed0e/10439_2023_3422_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c3/10940396/5b1a33f69b1f/10439_2023_3422_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c3/10940396/392c19b52dd2/10439_2023_3422_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c3/10940396/03fd257e7a39/10439_2023_3422_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c3/10940396/597465bdeb3a/10439_2023_3422_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c3/10940396/df8ea80a44f6/10439_2023_3422_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c3/10940396/0fa18638ed0e/10439_2023_3422_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c3/10940396/5b1a33f69b1f/10439_2023_3422_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c3/10940396/c33b7a94a2cd/10439_2023_3422_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c3/10940396/392c19b52dd2/10439_2023_3422_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c3/10940396/03fd257e7a39/10439_2023_3422_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c3/10940396/597465bdeb3a/10439_2023_3422_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c3/10940396/df8ea80a44f6/10439_2023_3422_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c3/10940396/0fa18638ed0e/10439_2023_3422_Fig7_HTML.jpg

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本文引用的文献

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A Machine Learning Approach to Screen for Otitis Media Using Digital Otoscope Images Labelled by an Expert Panel.一种使用由专家小组标注的数字耳镜图像进行中耳炎筛查的机器学习方法。
Diagnostics (Basel). 2022 May 25;12(6):1318. doi: 10.3390/diagnostics12061318.
2
Classification of Ear Imagery Database using Bayesian Optimization based on CNN-LSTM Architecture.基于 CNN-LSTM 架构的贝叶斯优化的耳部图像数据库分类。
J Digit Imaging. 2022 Aug;35(4):947-961. doi: 10.1007/s10278-022-00617-8. Epub 2022 Mar 16.
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Efficient and accurate identification of ear diseases using an ensemble deep learning model.
利用集成深度学习模型高效准确地识别耳部疾病。
Sci Rep. 2021 May 25;11(1):10839. doi: 10.1038/s41598-021-90345-w.
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