University of Victoria, School of Nursing, Director, Centre for Evidence informed Nursing and Health Care: JBI Centre of Excellence, Victoria, Canada.
Athabasca University, Chair, Ontario Cancer Research Ethics Board, Toronto, Canada.
PLoS One. 2023 Dec 15;18(12):e0295914. doi: 10.1371/journal.pone.0295914. eCollection 2023.
The objective of this scoping review is to map the available evidence on strategies that nurses can use to facilitate genomics-informed healthcare to address health disparities.
Advancements in genomics over the last two decades have led to an increase in the delivery of genomics-informed health care. Although the integration of genomics into health care services continues to enhance patient outcomes, access to genomic technologies is not equitable, exacerbating existing health disparities amongst certain populations. As the largest portion of the health workforce, nurses play a critical role in the delivery of equitable genomics-informed care. However, little is known about how nurses can help address health disparities within the context of genomics-informed health care. A review of the literature will provide the necessary foundation to identify promising practices, policy, and knowledge gaps for further areas of inquiry.
We will include papers that explore strategies that nurses can undertake to facilitate genomics-informed care to address health disparities.
This review will be conducted using JBI methodology for scoping reviews. We will search electronic databases including MEDLINE (OVID), EMBASE, Cochrane Library, PsychInfo, and CINAHL for quantitative and qualitative studies, systematic reviews and grey literature. Theses, books, and unavailable full-text papers will be excluded. The search will be limited to papers from 2013 and beyond. Two reviewers will screen titles and abstracts followed by full-text and disagreements will be resolved by a third reviewer. We will use a data extraction tool using Microsoft Excel and analyse data using descriptive statistics and conventional content analysis. Findings will be presented in the form of evidence tables and a narrative summary. We will report findings using the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR).
Genomics will continue to transform all aspects of health care across the wellness continuum from prevention, assessment, diagnosis, management, treatment, and palliative care. The identification of nursing strategies to address health disparities will build the foundation for policy and practice to ensure that the integration of genomic technologies benefits everyone.
本范围综述的目的是绘制现有证据，以了解护士可以用来促进以基因组信息为基础的医疗保健以解决健康差异的策略。
在过去的二十年中，基因组学的进步导致了更多的以基因组信息为基础的医疗保健的提供。尽管将基因组学纳入医疗保健服务继续提高患者的治疗效果，但获得基因组技术并不公平，这加剧了某些人群中现有的健康差异。作为最大的医疗保健劳动力的一部分，护士在提供公平的以基因组信息为基础的护理方面发挥着至关重要的作用。然而，对于护士如何帮助解决以基因组信息为基础的医疗保健方面的健康差异，我们知之甚少。对文献的回顾将为确定有前途的实践、政策和知识差距提供必要的基础，以进一步进行调查。
我们将包括探讨护士可以采取的策略，以促进以基因组信息为基础的护理，以解决健康差异的论文。
本综述将使用 JBI 方法进行范围综述。我们将搜索电子数据库，包括 MEDLINE（OVID）、EMBASE、Cochrane 图书馆、PsychInfo 和 CINAHL，以获取定量和定性研究、系统评价和灰色文献。将排除论文、书籍和无法获得全文的论文。搜索将限于 2013 年及以后的论文。两名审查员将筛选标题和摘要，然后进行全文筛选，如果出现分歧，将由第三名审查员解决。我们将使用 Microsoft Excel 的数据提取工具进行分析，并使用描述性统计和常规内容分析进行数据分析。研究结果将以证据表和叙述性摘要的形式呈现。我们将使用系统评价和荟萃分析扩展的首选报告项目（PRISMA-ScR）来报告发现。
基因组学将继续改变从预防、评估、诊断、管理、治疗和姑息治疗的整个健康保健连续体的所有方面。确定解决健康差异的护理策略将为政策和实践奠定基础，以确保基因组技术的整合使每个人受益。
