Department of Psychology and Neuroscience, Baylor University, Waco, Texas, USA.
Indiana University School of Nursing, Indianapolis, Indiana, USA.
Int J Clin Exp Hypn. 2024 Jan-Mar;72(1):16-28. doi: 10.1080/00207144.2023.2279672. Epub 2024 Feb 1.
Poor sleep quality is highly prevalent among individuals with mild cognitive impairment (MCI). Further, poor sleep quality is associated with reduced quality of life, increased stress response, memory impairments, and progression to dementia among individuals with MCI. Pharmacological treatments for sleep have mixed efficacy and can lead to dependency. Therefore, alternatives to pharmacological treatments for improving sleep among individuals with MCI are needed. The present study reports on the feasibility of a non-pharmacological self-administered hypnosis intervention focused on sleep quality in adults with MCI. It was hypothesized that the hypnosis intervention program would be feasible and have acceptable levels of adherence to daily hypnosis practice. A two-armed randomized controlled pilot trial was conducted using a sample of 21 adults with MCI. Eligible participants were randomly assigned to listen to either hypnosis audio recordings or sham hypnosis recordings for five weeks. Program feasibility, program adherence, pain intensity, stress, and sleep quality were measured using a daily home practice log, questionnaires, and wrist actigraphy. The results found mid or higher levels of treatment satisfaction, ease of use, and perceived effectiveness at one-week follow-up, with participants in the hypnosis arm reporting greater perceived benefit. Adherence to assigned audio recordings and meetings were likewise within acceptable margins in both groups. No intervention-related adverse events were reported in either treatment condition. Significant improvements in sleep quality, sleep duration, and daytime sleepiness were found for the hypnosis intervention. The results of this study can be used to inform future research on the effects of hypnosis on sleep quality in adults with MCI.
睡眠质量差在轻度认知障碍（MCI）患者中极为普遍。此外，睡眠质量差与生活质量下降、应激反应增加、记忆障碍以及 MCI 患者向痴呆发展有关。改善睡眠的药物治疗效果不一，且可能导致依赖性。因此，需要针对 MCI 患者的睡眠问题提供非药物治疗选择。本研究报告了一种针对 MCI 成年人睡眠质量的非药物自我催眠干预措施的可行性。假设催眠干预方案具有可行性，并且具有可接受的每日催眠练习依从性。一项为期五周的双臂随机对照试验使用了 21 名 MCI 成年人的样本。合格的参与者被随机分配到听催眠录音或假催眠录音组。使用每日家庭练习日志、问卷和腕部活动记录仪来测量方案的可行性、方案的依从性、疼痛强度、压力和睡眠质量。结果发现，在一周随访时，治疗满意度、易用性和感知效果处于中高水平，催眠组的参与者报告了更大的感知益处。在两组中，分配的录音和会议的依从性也在可接受的范围内。在任何治疗条件下都没有报告与干预相关的不良事件。催眠干预组的睡眠质量、睡眠时间和白天嗜睡均有显著改善。本研究结果可用于为未来关于催眠对 MCI 成年人睡眠质量影响的研究提供信息。
