Lukoff D, Liberman R P, Nuechterlein K H
Schizophr Bull. 1986;12(4):578-602. doi: 10.1093/schbul/12.4.578.
Although precise laboratory methods for measuring psychopathology are not available, interviewer-rated instruments developed to assess symptomatology can be used to monitor schizophrenic patients undergoing rehabilitation. By regularly assessing patients, rehabilitation staff can improve the effectiveness of their interventions. Patients can be screened for high levels of symptomatology which might preclude assignment to rehabilitation programs with high levels of social stimulation. Monitoring the prodromal symptoms of relapse can sometimes prevent florid relapses and sustain a rehabilitative trajectory. Standardized instruments for measuring positive symptoms (e.g., hallucinations, delusions, and conceptual disorganization) and negative symptoms (e.g., affective blunting, amotivation, and asociality) are available. Monitoring target symptoms may be particularly cost effective in the rehabilitation milieu. Use of suggested operational criteria for defining clinical states such as relapse would improve outcome studies on rehabilitation interventions.
虽然目前尚无精确测量精神病理学的实验室方法，但为评估症状而开发的访谈者评定工具可用于监测正在接受康复治疗的精神分裂症患者。通过定期评估患者，康复工作人员可以提高干预措施的有效性。可以对患者进行筛查，以确定其症状水平是否过高，这可能会妨碍他们参加具有高度社会刺激的康复项目。监测复发的前驱症状有时可以预防明显的复发，并维持康复进程。有标准化工具可用于测量阳性症状（如幻觉、妄想和概念紊乱）和阴性症状（如情感迟钝、缺乏动机和社交障碍）。在康复环境中监测目标症状可能特别具有成本效益。使用建议的操作标准来定义诸如复发等临床状态，将改善康复干预的结果研究。
