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健康老龄化：将因果机制与整体结果联系起来。

Healthy aging: Linking causal mechanisms with holistic outcomes.

机构信息

Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.

Department of Medicine, Virginia Tech Carilion School of Medicine, Roanoke, Virginia, USA.

出版信息

Aging Cell. 2024 Jan;23(1):e14065. doi: 10.1111/acel.14065. Epub 2023 Dec 18.

DOI:10.1111/acel.14065
PMID:38108552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10776108/
Abstract

Identifying and understanding the impact of differing exposures over the lifecourse necessitates contextualizing different levels of influence ranging from genetics, epigenetics, geography, and psychosocial networks.

摘要

确定和理解一生中不同暴露的影响需要从遗传学、表观遗传学、地理学和社会心理网络等不同层面的影响进行背景化分析。

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本文引用的文献

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Aging Cell. 2024 Jan;23(1):e14034. doi: 10.1111/acel.14034. Epub 2023 Dec 1.
2
Effect of canakinumab on frailty: A post hoc analysis of the CANTOS trial.卡那奴单抗对虚弱的影响：CANTOS 试验的事后分析。
Aging Cell. 2024 Jan;23(1):e14029. doi: 10.1111/acel.14029. Epub 2023 Nov 5.
3
Skeletal muscle DNA methylation: Effects of exercise and HIV.骨骼肌 DNA 甲基化：运动和 HIV 的影响。
Aging Cell. 2024 Jan;23(1):e14025. doi: 10.1111/acel.14025. Epub 2023 Nov 3.
4
Long-term Tai Chi practice in older adults is associated with "younger" functional abilities.长期练习太极拳可使老年人的身体机能“返老还童”。
Aging Cell. 2024 Jan;23(1):e14023. doi: 10.1111/acel.14023. Epub 2023 Oct 31.
5
Holistic care in healthy aging: Caring for the wholly and holy human.整体健康老龄化护理：关怀完整而神圣的人。
Aging Cell. 2024 Jan;23(1):e14021. doi: 10.1111/acel.14021. Epub 2023 Oct 24.
6
Integrated multicomponent interventions to support healthy aging of the whole person.综合性多组分干预措施，以支持整个人的健康老龄化。
Aging Cell. 2024 Jan;23(1):e14001. doi: 10.1111/acel.14001. Epub 2023 Oct 15.
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Associations of religious and existential variables with psychosocial factors and biomarkers of cardiovascular risk in bereavement.宗教和存在变量与丧亲之痛中心理社会因素和心血管风险生物标志物的关联。
Aging Cell. 2024 Jan;23(1):e14014. doi: 10.1111/acel.14014. Epub 2023 Oct 16.
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Senescent cells at the crossroads of aging, disease, and tissue homeostasis.衰老、疾病和组织稳态交汇处的衰老细胞。
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Holistic frailty prevention: The promise of movement-based mind-body therapies.整体虚弱预防：基于运动的身心疗法的前景。
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