Irving R A, Noakes T D, Rodgers A L, Swartz L
Urol Res. 1986;14(6):289-94. doi: 10.1007/BF00262377.
Epidemiological evidence suggests that marathon runners have a higher incidence of renal stone formation than occurs in the general population. Since crystalluria and stone disease are thought to be related, we subjected urine samples from a group of marathon runners to particle counting and sizing in a Coulter Counter equipped with a population accessory unit. The volume-size distribution curves so obtained were bimodal with one peak occurring in the 2-5 micron diameter range and a second in the 15-32 micron diameter range - a pattern that is remarkably similar to the distributions reported for recurrent idiopathic stone formers and distinctly different to those recorded for control subjects. Analyses by scanning electron microscopy and X-ray powder diffraction revealed other features which are regarded as typical of stone formers' crystalluria. These physicochemical data indicate that marathon runners may be at increased risk of urinary stone formation.
流行病学证据表明，马拉松运动员肾结石形成的发生率高于普通人群。由于结晶尿症和结石病被认为有关联，我们将一组马拉松运动员的尿液样本在配备群体辅助装置的库尔特计数器中进行颗粒计数和尺寸测定。由此获得的体积-尺寸分布曲线呈双峰状，一个峰值出现在直径2-5微米范围内，另一个出现在直径15-32微米范围内——这种模式与复发性特发性结石形成者报告的分布非常相似，与对照组记录的分布明显不同。通过扫描电子显微镜和X射线粉末衍射分析揭示了其他被认为是结石形成者结晶尿典型特征的特性。这些物理化学数据表明马拉松运动员可能有更高的尿路结石形成风险。
