Al-Mazidi Sarah H, ALRouq Fawzia, Alsabty Areej S, Alhajlah Abdullah, AlYahya Asma, Alsabih Ahmed, Al-Taweraqi Reema, Alahmari Abdullah S, Al-Dakhil Lina, Habib Syed
Physiology, Imam Mohammad Ibn Saud Islamic University, Riyadh, SAU.
Physiology, King Saud University, College of Medicine, Riyadh, SAU.
Cureus. 2023 Nov 17;15(11):e48980. doi: 10.7759/cureus.48980. eCollection 2023 Nov.
The neurological effect of viral respiratory infections has been acknowledged in many studies. However, patients who recovered from this infection show neurological manifestations and are not being routinely transferred for electrodiagnostic evaluation.
This study aimed to examine the neurological effect of viral respiratory infections on the nerve function using electrophysiology in patients fully recovered from viral respiratory infections.
To limit bias in the results, the authors decided to choose patients who recovered from one virus in all participants (coronavirus). Medical records were screened for patients who performed nerve conduction studies (NCSs) before the coronavirus pandemic. Thirty patients met our inclusion criteria, and only 10 showed up to perform NCS. Data of the NCS was compared before and after the coronavirus infection for motor and sensory NCS parameters.
An increase in both the median and ulnar sensory nerve latencies and a decrease in the sensory nerve amplitude was observed. Also, there was a decrease in the motor conduction velocity (MCV) of the ulnar nerves and motor amplitude in the median nerve. In the lower limbs, there was a decrease in the sural nerve latency, increased MCV in the tibial nerves, and decreased MCV in the peroneal nerves. The proximal amplitudes of the tibial and peroneal nerves were increased, but the distal amplitude was increased only in the peroneal nerves and decreased in the tibial nerves.
There is a significant impact of viral infections on the peripheral nerves. Large-scale prospective studies are required to investigate the pathogenesis of the neuropathy and myopathy after viral infections.
病毒感染性呼吸道疾病的神经学效应在许多研究中已得到公认。然而，从该感染中康复的患者表现出神经学症状，却未被常规转诊以进行电诊断评估。
本研究旨在通过电生理学检查病毒感染性呼吸道疾病康复患者的病毒感染对神经功能的影响。
为减少结果偏差，作者决定在所有参与者中选择仅感染一种病毒（冠状病毒）的康复患者。筛查在冠状病毒大流行之前进行神经传导研究（NCS）的患者的病历。30名患者符合纳入标准，但只有10名前来进行NCS。比较冠状病毒感染前后NCS的运动和感觉NCS参数数据。
观察到正中神经和尺神经感觉神经潜伏期均增加，感觉神经波幅降低。此外，尺神经的运动传导速度（MCV）降低，正中神经的运动波幅降低。在下肢，腓肠神经潜伏期缩短，胫神经MCV增加，腓总神经MCV降低。胫神经和腓总神经的近端波幅增加，但仅腓总神经的远端波幅增加，胫神经的远端波幅降低。
病毒感染对周围神经有显著影响。需要进行大规模前瞻性研究以调查病毒感染后神经病变和肌病的发病机制。
