Alghamdi Walid A, Alwesaibie Hussain S, Albesher Mohammed A, Alghamdi Fai K, Albaqshi Alreem A
Dermatology, Security Forces Hospital, Riyadh, SAU.
Medical School, King Faisal University, Al-Ahsa, SAU.
Cureus. 2023 Dec 14;15(12):e50516. doi: 10.7759/cureus.50516. eCollection 2023 Dec.
Background Acne vulgaris is a widespread chronic inflammatory dermatological disease with a worldwide prevalence of 9.4%, affecting a large percentage of the young population in the Kingdom of Saudi Arabia. This study aimed to measure the knowledge, attitude, and practice toward the use of isotretinoin among the Saudi population. Methodology This cross-sectional study was conducted among the general population in Saudi Arabia between April 2023 and July 2023. A self-administered questionnaire was distributed across five regions of Saudi Arabia (central, eastern, western, southern, and northern) using Google Survey. The questionnaire included sociodemographic data, the pattern of isotretinoin used, and a 24-item questionnaire to assess the knowledge about isotretinoin. Results Of the 3,001 participants, 77.1% were females, and 55.4% were aged between 16 and 25 years. The prevalence of participants who previously used isotretinoin was 30.6%. The total mean knowledge score was 10.4 (SD = 5.99) out of 24 points, with more than half (52.9%) considered to have poor knowledge, 39.1% moderate knowledge, and only 7.9% good knowledge. Younger participants, female gender, Saudi nationality, never been married, and previous use of isotretinoin were associated with increased knowledge. Conclusions The knowledge of the general population regarding isotretinoin use was lacking. However, younger Saudi females who had previous isotretinoin usage tended to be more knowledgeable about isotretinoin compared to the rest of the participants. Increasing the general public's knowledge regarding isotretinoin and its safe use is necessary.
背景 寻常痤疮是一种广泛存在的慢性炎症性皮肤病，全球患病率为9.4%，沙特阿拉伯王国很大一部分年轻人口受其影响。本研究旨在衡量沙特人群对异维A酸使用的知识、态度和实践情况。方法 本横断面研究于2023年4月至2023年7月在沙特阿拉伯的普通人群中进行。使用谷歌调查问卷在沙特阿拉伯的五个地区（中部、东部、西部、南部和北部）发放自填式问卷。问卷包括社会人口统计学数据、异维A酸的使用模式，以及一份用于评估对异维A酸知识的24项问卷。结果 在3001名参与者中，77.1%为女性，55.4%年龄在16至25岁之间。之前使用过异维A酸的参与者患病率为30.6%。在24分的总分中，知识得分的总平均分是10.4（标准差 = 5.99），超过一半（52.9%）的人被认为知识水平较差，39.1%为中等知识水平，只有7.9%为良好知识水平。年轻参与者、女性、沙特国籍、未婚以及之前使用过异维A酸与知识水平的提高相关。结论 普通人群对异维A酸使用的知识较为欠缺。然而，与其他参与者相比，之前使用过异维A酸的年轻沙特女性对异维A酸的了解往往更多。有必要提高公众对异维A酸及其安全使用的认识。
