内脂素如何用作高血压血管内皮功能障碍的特异性生物标志物？ - Suppr

How can endocan be used as a specific biomarker of endothelial dysfunction in hypertension?

作者信息

Hirooka Yoshitaka

机构信息

Department of Cardiovascular Medicine, International University of Health and Welfare Graduate School of Medicine, Okawa City, Fukuoka, Japan.

出版信息

Hypertens Res. 2024 Mar;47(3):794-795. doi: 10.1038/s41440-023-01542-1. Epub 2023 Dec 19.

DOI:10.1038/s41440-023-01542-1

PMID:38114652

Abstract

摘要

相似文献

How can endocan be used as a specific biomarker of endothelial dysfunction in hypertension?内脂素如何用作高血压血管内皮功能障碍的特异性生物标志物？

Hypertens Res. 2024 Mar;47(3):794-795. doi: 10.1038/s41440-023-01542-1. Epub 2023 Dec 19.

Endocan as a marker of endothelial dysfunction in hypertension: a systematic review and meta-analysis.内皮细胞蛋白聚糖作为高血压内皮功能障碍的标志物：系统评价和荟萃分析。

Hypertens Res. 2023 Oct;46(10):2388-2399. doi: 10.1038/s41440-023-01402-y. Epub 2023 Aug 14.

Endocan: A novel biomarker of endothelial dysfunction in depression?内皮细胞蛋白：抑郁症内皮功能障碍的新型生物标志物？

J Psychiatr Res. 2023 Sep;165:219-224. doi: 10.1016/j.jpsychires.2023.07.033. Epub 2023 Jul 21.

Relationship Between Obstructive Sleep Apnea Severity and Serum Endocan Levels in Patients With Hypertension.高血压患者阻塞性睡眠呼吸暂停严重程度与血清内皮素水平的关系。

Tex Heart Inst J. 2023 Jan 1;50(1). doi: 10.14503/THIJ-21-7664.

Serum endocan levels, carotid intima-media thickness and microalbuminuria in patients with newly diagnosed hypertension.血清内皮细胞黏附分子水平、颈动脉内膜中层厚度和新诊断高血压患者的微量白蛋白尿。

Clin Exp Hypertens. 2019;41(8):787-794. doi: 10.1080/10641963.2019.1652632. Epub 2019 Aug 7.

Could Endocan, a Marker of Inflammation and Endothelial Dysfunction, be a New Diagnostic Marker for Fibromyalgia?炎症和内皮功能障碍标志物内脂素能否成为纤维肌痛的新型诊断标志物？

Clin Lab. 2018 Mar 1;64(3):405-410. doi: 10.7754/Clin.Lab.2017.171024.

Endocan--a novel inflammatory indicator in newly diagnosed patients with hypertension: a pilot study.内皮细胞蛋白 C 受体——高血压初诊患者新型炎症标志物：一项初步研究。

Angiology. 2014 Oct;65(9):773-7. doi: 10.1177/0003319713513492. Epub 2014 Jan 8.

Endocan: A novel biomarker for risk stratification, prognosis and therapeutic monitoring in human cardiovascular and renal diseases.内脂素：人类心血管和肾脏疾病风险分层、预后及治疗监测的新型生物标志物。

Clin Chim Acta. 2020 Oct;509:310-335. doi: 10.1016/j.cca.2020.07.041. Epub 2020 Jul 22.

Endocan: A novel inflammatory indicator in cardiovascular disease?内脂素：心血管疾病中的一种新型炎症指标？

Atherosclerosis. 2015 Nov;243(1):339-43. doi: 10.1016/j.atherosclerosis.2015.09.030. Epub 2015 Sep 26.

Inflammation-induced increases in plasma endocan levels are associated with endothelial dysfunction in humans in vivo.炎症诱导的血浆内皮糖蛋白水平升高与人类体内的内皮功能障碍有关。

Shock. 2015 Apr;43(4):322-6. doi: 10.1097/SHK.0000000000000320.

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The predictive value of endocan as a novel biomarker: an umbrella study on meta-analyses.内皮糖蛋白作为一种新型生物标志物的预测价值：一项关于荟萃分析的综合研究。

Syst Rev. 2025 May 1;14(1):98. doi: 10.1186/s13643-025-02858-4.

Brain-Targeted Reactive Oxygen Species in Hypertension: Unveiling Subcellular Dynamics, Immune Cross-Talk, and Novel Therapeutic Pathways.高血压中的脑靶向活性氧：揭示亚细胞动力学、免疫相互作用及新型治疗途径

Antioxidants (Basel). 2025 Mar 28;14(4):408. doi: 10.3390/antiox14040408.

The Interplay Between Immunity, Inflammation and Endothelial Dysfunction.免疫、炎症与内皮功能障碍之间的相互作用

Int J Mol Sci. 2025 Feb 17;26(4):1708. doi: 10.3390/ijms26041708.

Endocan expression and correlation with other endothelial determinants in developing a score for early identification of diabetic peripheral neuropathy.在制定早期识别糖尿病周围神经病变的评分中，内脂素表达及其与其他内皮决定因素的相关性。

Sci Rep. 2025 Jan 5;15(1):850. doi: 10.1038/s41598-024-68790-0.

Current topic of vascular function in hypertension in 2023-2024.2023 - 2024年高血压血管功能的当前主题

Hypertens Res. 2024 Dec;47(12):3310-3317. doi: 10.1038/s41440-024-01885-3. Epub 2024 Sep 19.

本文引用的文献

Hypertens Res. 2023 Oct;46(10):2388-2399. doi: 10.1038/s41440-023-01402-y. Epub 2023 Aug 14.

Cardiovascular risk in patients receiving antihypertensive drug treatment from the perspective of endothelial function.从内皮功能的角度看接受降压药物治疗的患者的心血管风险。

Hypertens Res. 2022 Aug;45(8):1322-1333. doi: 10.1038/s41440-022-00936-x. Epub 2022 May 20.

Endocan: A Key Player of Cardiovascular Disease.内脂素：心血管疾病的关键因素

Front Cardiovasc Med. 2022 Jan 5;8:798699. doi: 10.3389/fcvm.2021.798699. eCollection 2021.

Endothelial Dysfunction and Atherosclerosis in Patients With Autosomal Dominant Polycystic Kidney Disease.常染色体显性多囊肾病患者的内皮功能障碍与动脉粥样硬化

Cureus. 2021 Feb 25;13(2):e13561. doi: 10.7759/cureus.13561.

Sympathetic Activation in Hypertension: Importance of the Central Nervous System.高血压中的交感神经激活：中枢神经系统的重要性。

Am J Hypertens. 2020 Oct 21;33(10):914-926. doi: 10.1093/ajh/hpaa074.

Endocan: a novel predictor of endothelial dysfunction in obstructive sleep apnea syndrome.内脂素：阻塞性睡眠呼吸暂停综合征中内皮功能障碍的一种新型预测指标。

Clin Respir J. 2018 Jan;12(1):84-90. doi: 10.1111/crj.12487. Epub 2016 May 24.

Angiotensin II receptor blockers improve endothelial dysfunction associated with sympathetic hyperactivity in metabolic syndrome.血管紧张素 II 受体阻滞剂改善代谢综合征伴交感神经活性亢进相关的内皮功能障碍。

J Hypertens. 2012 Aug;30(8):1646-55. doi: 10.1097/HJH.0b013e328355860e.

Endocan or endothelial cell specific molecule-1 (ESM-1): a potential novel endothelial cell marker and a new target for cancer therapy.内脂素或内皮细胞特异性分子-1（ESM-1）：一种潜在的新型内皮细胞标志物及癌症治疗的新靶点。

Biochim Biophys Acta. 2006 Jan;1765(1):25-37. doi: 10.1016/j.bbcan.2005.08.004. Epub 2005 Aug 26.

Endocan is a novel chondroitin sulfate/dermatan sulfate proteoglycan that promotes hepatocyte growth factor/scatter factor mitogenic activity.内脂素是一种新型硫酸软骨素/硫酸皮肤素蛋白聚糖，可促进肝细胞生长因子/分散因子的促有丝分裂活性。

J Biol Chem. 2001 Dec 21;276(51):48341-9. doi: 10.1074/jbc.M108395200. Epub 2001 Oct 5.

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How can endocan be used as a specific biomarker of endothelial dysfunction in hypertension?

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