Department of Gastroenterology, First Hospital of Quanzhou Affiliated to Fujian Medical University, Quanzhou, Fujian, China.
Medicine (Baltimore). 2023 Dec 15;102(50):e36629. doi: 10.1097/MD.0000000000036629.
We describe a rare case of a 54-year-old male diagnosed with both ulcerative colitis (UC) and hepatitis C virus (HCV), posing clinical challenges.
The patient showed worsened UC symptoms, leading to further evaluations.
Dual diagnosis of UC and HCV was confirmed through endoscopy and serological tests, ruling out other hepatic causes. Interventions: Treatment involved methylprednisolone for UC and sofosbuvir/velpatasvir for HCV, with attention to drug interactions.
Significant improvement was observed in both UC symptoms and HCV viral load post-treatment.
This case underscores the need for nuanced treatment in managing concurrent UC and HCV, considering potential drug interactions and disease impacts.
我们描述了一例罕见的 54 岁男性病例，他同时被诊断患有溃疡性结肠炎（UC）和丙型肝炎病毒（HCV），这给临床治疗带来了挑战。
患者的 UC 症状恶化，需要进一步评估。
通过内镜检查和血清学检测，确诊为 UC 和 HCV 的双重诊断，排除了其他肝脏病因。
针对 UC 采用了甲泼尼龙治疗，针对 HCV 采用了索磷布韦/维帕他韦治疗，并注意药物相互作用。
治疗后，UC 症状和 HCV 病毒载量均显著改善。
该病例强调了在治疗同时患有 UC 和 HCV 的患者时需要细致考虑，包括潜在的药物相互作用和疾病影响。
