Department of Neurology, Chongming Hospital Affiliated to Shanghai University of Medicine and Health Sciences, Shanghai, China.
Department of Neurosurgery, Chongming Hospital Affiliated to Shanghai University of Medicine and Health Sciences, Shanghai, China.
Medicine (Baltimore). 2023 Dec 15;102(50):e36199. doi: 10.1097/MD.0000000000036199.
Tinnitus is a common otological symptom affecting almost all aspects of life, especially the quality of daily life. The present study aims to analyze music therapy effect on tinnitus patients. This paper mainly analyzes 3 kinds of music therapy: Heidelberg model of music therapy (HMOMT), standard music therapy (SMT), and tailor-made notched music training (TMNMT). To provide a reference for the follow-up treatment of tinnitus, whether to take and what kind of music therapy.
A systematic literature search was performed in PubMed, Cochrane Library, EMBASE, Web of Science, and MEDLINE to obtain potential studies from their inception to May 2023 in all languages. Two researchers independently screened the studies, extracted data, and assessed the quality of the included studies. We included all randomized and non-randomized controlled trials that used music therapy to treat patients with tinnitus. We used fixed-effects and random-effect models to analyze data based on the heterogeneity results. The data analysis was performed by using Stata 12.0.
A total of 19 studies with 904 cases were included. Compared with before treatment, music therapy significantly reduces the tinnitus questionnaire score and tinnitus handicap inventory score. HMOMT, SMT, and TMNMT all significantly decrease tinnitus scores. Although the order of effectiveness of the 3 drugs is TMNMT > SMT > HMOMT, there is no statistical significance (P > .5).
This meta-analysis of accumulated clinical trial data suggests that music therapy can relieve tinnitus symptoms and loudness. Among music therapies, SMT is recommended first for tinnitus based on cost, efficacy, and convenience. At the same time, TMNMT and HMOMT can be used as alternative therapies for specific cases.
耳鸣是一种常见的耳科症状，几乎影响生活的方方面面，尤其是日常生活质量。本研究旨在分析音乐疗法对耳鸣患者的影响。本文主要分析了 3 种音乐疗法：海德堡音乐治疗模式（HMOMT）、标准音乐疗法（SMT）和定制有缺口音乐训练（TMNMT）。为耳鸣的后续治疗提供参考，是否采用以及采用何种音乐疗法。
系统检索 PubMed、Cochrane Library、EMBASE、Web of Science 和 MEDLINE 数据库，从建库至 2023 年 5 月，检索所有语言发表的潜在研究。由 2 位研究者独立筛选研究、提取资料并评价纳入研究的质量。纳入使用音乐疗法治疗耳鸣患者的随机和非随机对照试验。根据异质性结果，采用固定效应模型和随机效应模型进行数据分析。采用 Stata 12.0 进行数据分析。
共纳入 19 项研究，共 904 例患者。与治疗前相比，音乐疗法显著降低耳鸣问卷评分和耳鸣残疾量表评分。HMOMT、SMT 和 TMNMT 均显著降低耳鸣评分。虽然 3 种药物的疗效排序为 TMNMT>SMT>HMOMT，但无统计学意义（P>.5）。
该累积临床试验数据的荟萃分析表明，音乐疗法可以缓解耳鸣症状和响度。在音乐疗法中，基于成本、疗效和便利性，首先推荐 SMT 用于耳鸣。同时，TMNMT 和 HMOMT 可作为特定病例的替代疗法。
