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多灶性颈部血管平滑肌脂肪瘤。

Multinodal Cervical Angiomyomatous Hamartoma.

机构信息

Department of Health Science, The University of Auckland Faculty of Medical and Health Sciences, Auckland, New Zealand.

Department of Surgery, The University of Auckland, Auckland, New Zealand.

出版信息

Int J Surg Pathol. 2024 Sep;32(6):1129-1133. doi: 10.1177/10668969231212429. Epub 2023 Nov 20.

Abstract

Angiomyomatous hamartoma (AMH) is a rare benign lesion of the lymph nodes. Angiomyomatous hamartoma tends to be found in inguinal lymph nodes, and usually in a single lymph node. We present a rare care case of a 53-year-old presenting with a neck lump, found to be AMH involving multiple lymph nodes in her neck. To our knowledge, this is the first case presenting with multiple nodes in this location. There are a limited number of case reports describing magnetic resonance imaging (MRI) features of AMH lesions located in inguinal and head and neck regions. Our MRI findings revealed the mass had intermediate T1 enhancement, high T2 signal enhancement, and high post-gadolinium enhancement and fat saturation of the lesion. Angiomyomatous hamartoma is a histological diagnosis, distinguished from other similar nodal vascular lesions by a number of key features: including the presence of central nodal distribution, muscular blood vessel walls, adipose tissue, and HMB45 negative staining. Early recognition of this benign lesion may have implications for a patient's clinical course and surgical requirements.

摘要

血管肌纤维母细胞瘤(angiomyomatous hamartoma,AMH)是一种罕见的淋巴结良性病变。AMH 倾向于发生在腹股沟淋巴结,通常为单个淋巴结。我们报告了一例罕见的病例,一名 53 岁女性因颈部肿块就诊,发现颈部多个淋巴结受累。据我们所知,这是首例发生在该部位的多灶性病例。有少数病例报告描述了位于腹股沟和头颈部区域的 AMH 病变的磁共振成像(MRI)特征。我们的 MRI 结果显示肿块在 T1 增强时有中等程度的增强,在 T2 信号增强时有高信号,并且病变在钆增强后和脂肪饱和时有高信号增强。血管肌纤维母细胞瘤是一种组织学诊断,通过一些关键特征与其他类似的淋巴结血管病变区分开来:包括中央淋巴结分布、肌肉血管壁、脂肪组织和 HMB45 阴性染色。早期识别这种良性病变可能对患者的临床过程和手术需求有影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ae/11337725/c0caee91528e/10.1177_10668969231212429-fig1.jpg

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