Wang Ling, Pan Jun-Yu
Intensive Care Unit, People's Hospital of Qiandongnan Miao and Dong Autonomous Prefecture, Kaili 556000, Guizhou Province, China.
World J Clin Cases. 2024 Aug 6;12(22):4865-4872. doi: 10.12998/wjcc.v12.i22.4865.
Postpartum hemorrhage (PPH) is a leading cause of maternal mortality, and hysterectomy is an important intervention for managing intractable PPH. Accurately predicting the need for hysterectomy and taking proactive emergency measures is crucial for reducing mortality rates.
To develop a risk prediction model for PPH requiring hysterectomy in the ethnic minority regions of Qiandongnan, China, to help guide clinical decision-making.
The study included 23490 patients, with 1050 having experienced PPH and 74 who underwent hysterectomies. The independent risk factors closely associated with the necessity for hysterectomy were analyzed to construct a risk prediction model, and its predictive efficacy was subsequently evaluated.
The proportion of hysterectomies among the included patients was 0.32% (74/23490), representing 7.05% (74/1050) of PPH cases. The number of deliveries, history of cesarean section, placenta previa, uterine atony, and placenta accreta were identified in this population as independent risk factors for requiring a hysterectomy. Receiver operating characteristic curve analysis of the prediction model showed an area under the curve of 0.953 (95% confidence interval: 0.928-0.978) with a sensitivity of 90.50% and a specificity of 90.70%.
The model demonstrates excellent predictive power and is effective in guiding clinical decisions regarding PPH in the ethnic minority regions of Qiandongnan, China.
产后出血(PPH)是孕产妇死亡的主要原因,子宫切除术是治疗难治性PPH的重要干预措施。准确预测子宫切除术的需求并采取积极的紧急措施对于降低死亡率至关重要。
建立中国黔东南少数民族地区需要子宫切除术的PPH风险预测模型,以帮助指导临床决策。
该研究纳入23490例患者,其中1050例发生PPH,74例行子宫切除术。分析与子宫切除术必要性密切相关的独立危险因素,构建风险预测模型,并随后评估其预测效能。
纳入患者中子宫切除术的比例为0.32%(74/23490),占PPH病例的7.05%(74/1050)。该人群中分娩次数、剖宫产史、前置胎盘、宫缩乏力和胎盘植入被确定为需要子宫切除术的独立危险因素。预测模型的受试者工作特征曲线分析显示曲线下面积为0.953(95%置信区间:0.928 - 0.978),灵敏度为90.50%,特异度为90.70%。
该模型具有出色的预测能力,可有效指导中国黔东南少数民族地区关于PPH的临床决策。