Suna Gonca, Mellor Greg J
Cardiology Department, Royal Papworth Hospital NHS Foundation Trust Cambridge, UK.
Arrhythm Electrophysiol Rev. 2023 Nov 23;12:e27. doi: 10.15420/aer.2023.06. eCollection 2023.
Sudden cardiac arrest (SCA) is a common cause of death. The majority of SCA is caused by ventricular arrhythmia due to underlying CHD. Aborted SCA with no apparent diagnosis after initial assessment with ECG, echocardiography and coronary assessment is referred to as unexplained cardiac arrest (UCA). Systematic evaluation of such patients may reveal a specific diagnosis in up to half of patients before a diagnosis of idiopathic VF is assigned. Specific diagnoses include inherited cardiac conditions, such as latent cardiomyopathies or inherited primary electrical disease. Identifying the cause of UCA is therefore not only critical for appropriate management of the SCA survivors to prevent recurrence, but also for their family members who may be at risk of the same condition. This review provides a tiered, systematic approach for the investigation of UCA.
心脏骤停（SCA）是常见的死亡原因。大多数SCA是由潜在冠心病导致的室性心律失常引起的。经心电图、超声心动图和冠状动脉评估进行初步评估后，无明显诊断的心脏骤停未遂称为不明原因心脏骤停（UCA）。对这类患者进行系统评估，在诊断为特发性室颤之前，多达一半的患者可能会发现特定诊断。特定诊断包括遗传性心脏疾病，如隐匿性心肌病或遗传性原发性心电疾病。因此，确定UCA的病因不仅对于SCA幸存者的适当管理以预防复发至关重要，对于可能有相同疾病风险的家庭成员也很重要。本综述提供了一种分层、系统的方法来调查UCA。
