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心脏磁共振成像对心脏骤停后患者的诊断价值及临床影响:一项回顾性研究

Diagnostic value and clinical impact of cardiac magnetic resonance imaging in patients after sudden cardiac arrest: a retrospective study.

作者信息

Boxhammer Elke, Rezar Richard, Hecht Stefan, Knapitsch Christoph, Schörghofer Nikolaos, Strohmer Bernhard, Kaufmann Reinhard, Hoppe Uta C, Hergan Klaus, Scharinger Bernhard

机构信息

Department of Internal Medicine II, Paracelsus Medical University of Salzburg, Salzburg, Austria.

Department of Radiology, Paracelsus Medical University of Salzburg, Salzburg, Austria.

出版信息

Open Heart. 2025 May 14;12(1):e003090. doi: 10.1136/openhrt-2024-003090.

Abstract

INTRODUCTION

Cardiac MRI (CMRI) is an important investigation in cases of unclear cause of sudden cardiac arrest (SCA). It demonstrates diagnostic utility in assessing reversibility and tissue scar burden and ultimately aids in further treatment planning.

METHODS

A retrospective analysis of all adult patients referred for CMRI after SCA between 2007 and 2022 by local intensive care units in our institution was performed. The patient cohort is highly selective, excluding those who did not reach the hospital, had cerebral oedema or had confirmed acute myocardial infarction as the cause of SCA. Data on clinical presentation, imaging findings and subsequent management were collected and analysed.

RESULTS

CMRI was diagnostic in 57 of 65 patients. The most common diagnosis by CMRI was ischaemic cardiomyopathy (28.1%), followed by dilated cardiomyopathy (17.5%) and structurally normal hearts (14%). In cases of myocardial oedema, extracellular volume (ECV) was determined in 10 patients and found to be elevated in 80% after resuscitation, whereas T2 mapping was elevated in only 50% of cases. The number of examinations has increased, whereas the time to examination has decreased over the years. Additionally, CMRI findings led to changes in treatment planning.

CONCLUSION

CMRI after resuscitation is gaining increasing interest and clinical relevance as it provides additional diagnostic information that may be crucial for therapy planning. The sensitivity of ECV in detecting myocardial oedema after cardiac arrest highlights its potential utility over T2 mapping. Future studies should investigate the impact of CMRI on long-term patient outcomes and further refine its role in guiding treatment decisions.

摘要

引言

心脏磁共振成像(CMRI)对于不明原因的心源性猝死(SCA)病例是一项重要的检查。它在评估可逆性和组织瘢痕负荷方面具有诊断价值,并最终有助于进一步的治疗规划。

方法

对2007年至2022年间由我院当地重症监护病房转介进行CMRI检查的所有成年SCA患者进行回顾性分析。患者队列具有高度选择性,排除未送达医院、有脑水肿或已确诊急性心肌梗死作为SCA病因的患者。收集并分析临床表现、影像学检查结果及后续治疗的数据。

结果

65例患者中,CMRI具有诊断价值的有57例。CMRI最常见的诊断是缺血性心肌病(28.1%),其次是扩张型心肌病(17.5%)和结构正常的心脏(14%)。在心肌水肿的病例中,对10例患者测定了细胞外容积(ECV),发现复苏后80%的患者ECV升高,而T2 mapping仅在50%的病例中升高。多年来,检查次数增加,而检查时间减少。此外,CMRI检查结果导致了治疗方案的改变。

结论

复苏后的CMRI越来越受到关注,且具有临床相关性,因为它提供了可能对治疗规划至关重要的额外诊断信息。ECV在检测心脏骤停后心肌水肿方面的敏感性突出了其相对于T2 mapping的潜在效用。未来的研究应调查CMRI对患者长期预后的影响,并进一步明确其在指导治疗决策中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e264/12083315/5f98c685f2f6/openhrt-12-1-g001.jpg

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