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Maternal Exposure to Arsenic and Its Impact on Maternal and Fetal Health: A Review.

作者信息

Ortiz-Garcia Nancy Y, Cipriano Ramírez Anayansi Ixchel, Juarez Karen, Brand Galindo Jazmin, Briceño Gabriela, Calderon Martinez Ernesto

机构信息

General Medicine, Universidad Juárez del Estado de Durango, Durango, MEX.

General Practice, Instituto Politécnico Naciónal, Mexico City, MEX.

出版信息

Cureus. 2023 Nov 21;15(11):e49177. doi: 10.7759/cureus.49177. eCollection 2023 Nov.


DOI:10.7759/cureus.49177
PMID:38130554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10734558/
Abstract

Arsenic exposure is a significant public health issue, with harmful effects caused by its use in commercial products such as car batteries, pesticides, and herbicides. Arsenic has three main compounds: inorganic, organic, and arsine gas. Inorganic arsenic compounds in water are highly toxic. The daily intake of arsenic from food and beverages is between 20 and 300 mcg/day. Arsenic is known for its carcinogenic properties and is classified as a human carcinogen by different institutions. Exposure can lead to oxidative stress, DNA damage, and epigenetic deregulation, which can cause endocrine disorders, altered signal transduction pathways, and cell proliferation. In addition, arsenic can easily cross the placenta, making it a critical concern for maternal and fetal health. Exposure can lead to complications such as gestational diabetes, anemia, low birth weight, miscarriage, and congenital anomalies. Female babies are particularly vulnerable to the negative impact of arsenic exposure, with a higher risk of low weight for gestational age and congenital cardiac anomalies. Therefore, it is crucial to monitor and regulate the levels of arsenic in drinking water and food sources to prevent these adverse health outcomes. Further research is necessary to fully understand the impact of arsenic exposure on human health, especially during pregnancy and infancy, by implementing preventative measures and monitoring the levels of arsenic in the environment.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d4/10734558/06099889ad65/cureus-0015-00000049177-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d4/10734558/d52afd67acb9/cureus-0015-00000049177-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d4/10734558/06099889ad65/cureus-0015-00000049177-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d4/10734558/d52afd67acb9/cureus-0015-00000049177-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0d4/10734558/06099889ad65/cureus-0015-00000049177-i02.jpg

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Maternal Exposure to Arsenic and Its Impact on Maternal and Fetal Health: A Review.

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Environ Geochem Health. 2025-7-30

[2]
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[3]
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[4]
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[5]
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[6]
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[7]
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[8]
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[9]
Dynamics of Spatiotemporal Variation of Groundwater Arsenic in Central Rift Vally of Ethiopia: A Serial Cross-Sectional Study.

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[10]
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Pediatr Res. 2025-2

本文引用的文献

[1]
Placental levels of essential and non-essential trace element in relation to neonatal weight in Northwestern Spain: application of generalized additive models.

Environ Sci Pollut Res Int. 2023-5

[2]
Metabolic and genetic derangement: a review of mechanisms involved in arsenic and lead toxicity and genotoxicity.

Arh Hig Rada Toksikol. 2022-12-1

[3]
Progesterone: The Key Factor of the Beginning of Life.

Int J Mol Sci. 2022-11-16

[4]
Basal cell carcinoma-clinico-pathological study in Eastern India in correlation with different risk factors.

Indian J Pathol Microbiol. 2022

[5]
Prevalence of type 2 diabetes mellitus in relation to arsenic exposure and metabolism in Mexican women.

Environ Res. 2022-7

[6]
Arsenic exposure during pregnancy and postpartum maternal glucose tolerance: evidence from Bangladesh.

Environ Health. 2022-1-14

[7]
Arsenic exposure and non-carcinogenic health effects.

Hum Exp Toxicol. 2021-12

[8]
Blood Arsenic Levels as a Marker of Breast Cancer Risk among Carriers.

Cancers (Basel). 2021-7-3

[9]
Seven potential sources of arsenic pollution in Latin America and their environmental and health impacts.

Sci Total Environ. 2021-8-1

[10]
Metallothionein Attenuated Arsenic-Induced Cytotoxicity: The Underlying Mechanism Reflected by Metabolomics and Lipidomics.

J Agric Food Chem. 2021-5-12

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