Yavagal Chandrashekar Murugesh, Subramani Srinivas K, Patil Viplavi Chavan, Yavagal Puja C, Talwar Ramachandra P, Hebbal Mamata Iranna, Saadaldin Selma A, Eldwakhly Elzahraa, Abdelhafeez Manal M, Soliman Mai
Department of Pediatric Dentistry, Maratha Mandal's Nathajirao G. Halgekar Institute of Dental Sciences & Research Centre, Belgaum 590019, Karnataka, India.
Department of Public Health Dentistry, Bapuji Dental College and Hospital, Davanagere 577004, Karnataka, India.
Children (Basel). 2023 Dec 3;10(12):1887. doi: 10.3390/children10121887.
Photoactivated disinfection with sodium hypochlorite (NaOCl) has improved primary root canal treatment outcomes. This in vitro study aims to assess and compare the disinfecting efficacy of 2.5% sodium hypochlorite solution and 5.25% sodium hypochlorite gel, without laser activation and accompanied by laser activation, on -contaminated primary teeth root canals. After one month of incubating extracted teeth specimens with , 36 specimens were randomly divided into two groups: Group A (conventional method without laser-activated irrigation) and Group B (with laser-activated irrigation). Each group was further divided into three subgroups, with six samples in each subgroup. Subgroup 1 received irrigation with normal saline, Subgroup 2 with 2.5% sodium hypochlorite solution, and Subgroup 3 with 5.25% sodium hypochlorite gel. Diode laser activation at 810 nm was used in Group B. Bacterial colony counts were measured before and after the intervention. Student's -test and one-way analysis of variance (ANOVA) with Tukey's post hoc test were used for statistical analysis. The significance level was set at < 0.05. Microbial analysis revealed no bacterial growth in samples irrigated with 5.25% sodium hypochlorite gel activated with the laser. Activation with the laser significantly ( = 0.02) improved the disinfection ability of the irrigant compared to the non-activation group. The disinfection ability of sodium hypochlorite gel was better than that of saline ( = 0.02); however, it was comparable to that of sodium hypochlorite solution ( = 0.67). Conclusion: Root canal irrigation with 5.25% sodium hypochlorite gel activated with an 810 nm diode laser resulted in complete eradication of , indicating its effectiveness as an endodontic disinfection treatment modality.
次氯酸钠（NaOCl）光活化消毒改善了乳牙根管治疗的效果。本体外研究旨在评估和比较2.5%次氯酸钠溶液和5.25%次氯酸钠凝胶在未进行激光激活以及进行激光激活的情况下，对污染的乳牙根管的消毒效果。在用[具体物质]孵育提取的牙齿标本一个月后，将36个标本随机分为两组：A组（未进行激光激活冲洗的传统方法）和B组（进行激光激活冲洗）。每组再进一步分为三个亚组，每个亚组有六个样本。亚组1用生理盐水冲洗，亚组2用2.5%次氯酸钠溶液冲洗，亚组3用5.25%次氯酸钠凝胶冲洗。B组使用810nm二极管激光进行激活。在干预前后测量细菌菌落计数。采用学生t检验和带有Tukey事后检验的单因素方差分析（ANOVA）进行统计分析。显著性水平设定为<0.05。微生物分析显示，用激光激活的5.25%次氯酸钠凝胶冲洗的样本中没有细菌生长。与未激活组相比，激光激活显著（P = 0.02）提高了冲洗液的消毒能力。次氯酸钠凝胶的消毒能力优于生理盐水（P = 0.02）；然而，它与次氯酸钠溶液的消毒能力相当（P = 0.67）。结论：用810nm二极管激光激活的5.25%次氯酸钠凝胶进行根管冲洗可完全根除[具体细菌名称]，表明其作为一种牙髓消毒治疗方式的有效性。
