Ott D A, Garson A, Cooley D A, Smith R T, Moak J
Ann Thorac Surg. 1987 Feb;43(2):138-43. doi: 10.1016/s0003-4975(10)60382-7.
Of 175 patients treated surgically for potentially lethal or refractory cardiac tachyarrhythmias, 53 underwent mapping and definitive operation using cryoablative techniques as the primary or adjunctive method. Included were 16 patients with supraventricular tachycardia caused by accessory pathways (Kent bundle) in the right anterior or posterior paraseptal location. Cryoablation was successful in abolishing tachycardia in 93.7% (15 of 16). Six patients (100%) with permanent junctional reciprocating tachycardia were cured by cryoablation. Eighteen of 19 patients with atrial ectopic tachycardia were treated by cryoablation alone or in combination with excision of the atrial appendage, with success in 15 (83.3%). Five of these were left atrial foci cured by cryoablation. Fourteen right atrial foci were treated by excision of the appendage only (1 patient), excision of the appendage and local cryoablation (8 patients), and cryoablation alone (5 patients). Three of these underwent partial (2 patients) or complete (1 patient) atrial disconnection after excisional and cryoablative techniques failed to control the tachycardia. Multiple ectopic atrial foci were common (9 patients), and successful cryoablation was accomplished in 100% of the patients with a single atrial ectopic focus (10 patients) but in only 66% of those with multiple foci. Thirteen of 19 infants with critical ventricular tachycardia were treated by cryoablation at the site of the ectopic focus, either alone or in combination with excision of the area. Elimination of tachycardia was accomplished in 13 patients (100%). Myocardial hamartoma (Purkinje cell tumor) was the histological diagnosis in 11 of the infants with ventricular tachycardia.(ABSTRACT TRUNCATED AT 250 WORDS)
在175例因潜在致命性或难治性心脏快速性心律失常接受手术治疗的患者中,53例采用冷冻消融技术作为主要或辅助方法进行标测和确定性手术。其中包括16例右前或后间隔旁道(肯特束)引起的室上性心动过速患者。冷冻消融成功消除心动过速的比例为93.7%(16例中的15例)。6例永久性交界性反复性心动过速患者(100%)通过冷冻消融治愈。19例房性异位性心动过速患者中的18例接受了单独冷冻消融或联合心房附件切除术治疗,15例(83.3%)成功。其中5例左心房病灶通过冷冻消融治愈。14例右心房病灶仅接受附件切除术(1例患者)、附件切除术和局部冷冻消融(8例患者)以及单独冷冻消融(5例患者)治疗。其中3例在切除和冷冻消融技术未能控制心动过速后接受了部分(2例患者)或完全(1例患者)心房离断术。多个异位心房病灶很常见(9例患者),单个房性异位病灶患者(10例患者)冷冻消融成功率为100%,但多个病灶患者仅为66%。19例重症室性心动过速婴儿中的13例在异位病灶部位接受了冷冻消融治疗,单独或联合该区域切除术。13例患者(100%)实现了心动过速消除。11例室性心动过速婴儿的组织学诊断为心肌错构瘤(浦肯野细胞瘤)。(摘要截选至250词)