Stan Gabriel, Roman Mihai Dan, Orban Horia, Georgeanu Vlad Alexandru, Deculescu Rares Stefan, Brinduse Lacramioara Aurelia, Gheorghiu Nicolae
Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Faculty of Medicine, University "Lucian Blaga" of Sibiu, 550024 Sibiu, Romania.
J Clin Med. 2023 Dec 5;12(24):7506. doi: 10.3390/jcm12247506.
To reduce the incidence of total hip revisions, there have been continuous efforts to enhance prosthetic materials and designs to optimize implant survival. A primary implant with a constrained acetabular component is often used to minimize the risk of dislocations even though this approach has some drawbacks as reported in the literature. To address these concerns, this study aimed to assess the survivorship and dislocation rate of a semi-retentive cemented acetabular cup when used as a primary implant. The specific cemented cup that we studied was not present in any study that we consulted, so to fill this gap, we conducted a retrospective examination of 527 cemented hip prostheses that utilized the semi-retentive cup between the years 2005 and 2012. We employed Cox multiple regression models for our statistical analysis. The revision due to dislocation occurred in 12.8% of all cases, with a lower incidence of 5% (14 cases) in age groups >70 years than in age groups <70 years (14%-32 cases) ( < 0.001). The survival rates of the semi-retentive cemented acetabular cup were 98.6% (520 cases) at 5 years and 92.2% (487 cases) at 10 years. The survival rates were significantly lower in women than men, with 1.9% (7 cases) toward 0% at 5 years and 8.1% (30 cases) toward 5% (7 cases) at 10 years ( = 0.002). The difference in failure rates between age groups over 70 years (2.3%-10 cases) and age groups under 70 years (11.5%-34 cases) was also statistically significant ( < 0.001). Our study indicates that the semi-constrained design may cause frequent damage to the polyethylene liner due to impingement and wear, which are the primary factors for failure. Also, this implant has a similar risk of revision due to dislocation as reported in studies and may be beneficial as a primary implant in elderly patients with low-demanding lifestyles, muscular insufficiency, and low compliance regarding hip prosthetic behavior, without a major effect on survivorship.
为降低全髋关节翻修的发生率,人们不断努力改进假体材料和设计,以优化植入物的使用寿命。尽管文献报道这种方法存在一些缺点,但带有受限髋臼组件的初次植入物常被用于将脱位风险降至最低。为解决这些问题,本研究旨在评估半固定式骨水泥髋臼杯作为初次植入物时的生存率和脱位率。我们研究的特定骨水泥杯在我们查阅的任何研究中均未出现,因此为填补这一空白,我们对2005年至2012年间使用半固定式杯的527例骨水泥髋关节假体进行了回顾性检查。我们采用Cox多元回归模型进行统计分析。所有病例中因脱位导致的翻修发生率为12.8%,年龄>70岁组的发生率为5%(14例),低于年龄<70岁组(14% - 32例)(<0.001)。半固定式骨水泥髋臼杯的5年生存率为98.6%(520例),10年生存率为92.2%(487例)。女性的生存率显著低于男性,5年时从1.9%(7例)降至0%,10年时从8.1%(30例)降至5%(7例)(=0.002)。70岁以上年龄组(2.3% - 10例)和70岁以下年龄组(11.5% - 34例)的失败率差异也具有统计学意义(<0.001)。我们的研究表明,半约束设计可能会因撞击和磨损而频繁损坏聚乙烯内衬,这是失败的主要因素。此外,这种植入物因脱位导致翻修的风险与研究报道相似,对于生活需求低、肌肉功能不全且对髋关节假体行为依从性低的老年患者,作为初次植入物可能有益,且对生存率无重大影响。