Sanftenberg Linda, Keppeler Simon, Heithorst Nadine, Dreischulte Tobias, Roos Marco, Sckopke Philipp, Bühner Markus, Gensichen Jochen
Institute of General Practice and Family Medicine, University Hospital, LMU Munich, 80336 Munich, Germany.
General Practice, Medical Faculty, University of Augsburg, 86356 Neusäß, Germany.
Vaccines (Basel). 2023 Nov 30;11(12):1795. doi: 10.3390/vaccines11121795.
Vaccines against COVID-19 and influenza are highly recommended for the chronically ill. They often suffer from co-morbid mental health issues. This cross-sectional observational study analyzes the associations between depression (PHQ-9) and anxiety (OASIS) with vaccination readiness (5C) against COVID-19 and influenza in chronically ill adults in primary care in Germany. Sociodemographic data, social activity (LSNS), patient activation measure (PAM), and the doctor/patient relationship (PRA) are examined as well. Descriptive statistics and linear mixed-effects regression models are calculated. We compare data from = 795 study participants. The symptoms of depression are negatively associated with confidence in COVID-19 vaccines ( = 0.010) and positively associated with constraints to get vaccinated against COVID-19 ( = 0.041). There are no significant associations between symptoms of depression and vaccination readiness against influenza. Self-reported symptoms of a generalized anxiety disorder seem not to be associated with vaccination readiness. To address confidence in COVID-19 vaccines among the chronically ill, targeted educational interventions should be elaborated to consider mental health issues like depression. As general practitioners play a key role in the development of a good doctor/patient relationship, they should be trained in patient-centered communication. Furthermore, a standardized implementation of digital vaccination management systems might improve immunization rates in primary care.
强烈建议慢性病患者接种新冠疫苗和流感疫苗。他们常常伴有心理健康问题。这项横断面观察性研究分析了德国初级保健机构中慢性病成年患者的抑郁（PHQ-9）和焦虑（OASIS）与新冠疫苗和流感疫苗接种意愿（5C）之间的关联。同时还研究了社会人口统计学数据、社交活动（LSNS）、患者激活度量（PAM）以及医患关系（PRA）。计算了描述性统计数据和线性混合效应回归模型。我们比较了795名研究参与者的数据。抑郁症状与对新冠疫苗的信心呈负相关（P = 0.010），与接种新冠疫苗的限制呈正相关（P = 0.041）。抑郁症状与流感疫苗接种意愿之间没有显著关联。自我报告的广泛性焦虑症症状似乎与接种意愿无关。为了增强慢性病患者对新冠疫苗的信心，应制定有针对性的教育干预措施，以考虑抑郁等心理健康问题。由于全科医生在建立良好医患关系方面起着关键作用，他们应接受以患者为中心的沟通培训。此外，标准化实施数字疫苗管理系统可能会提高初级保健机构的免疫接种率。
