Department of Otolaryngology-Head and Neck Surgery, Hsinchu Hospital, China Medical University, Hsinchu, Taiwan.
School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan.
Otolaryngol Head Neck Surg. 2024 Mar;170(3):675-693. doi: 10.1002/ohn.597. Epub 2023 Dec 22.
Our objective was to perform a systematic review and meta-analysis comparing the clinical outcomes after endoscopic and microscopic type I tympanoplasty.
Randomized controlled trials, two-arm prospective studies, and retrospective studies were included.
Medline, Cochrane, EMBASE, and Google Scholar databases were searched until March 1, 2022 using the combinations of search terms: "endoscopic," "microscopic," and "tympanoplasty."
Two independent reviewers utilized the abovementioned search strategy to identify eligible studies. If any uncertainty existed regarding eligibility, a third reviewer was consulted. Primary outcome measures were graft success rate, air-bone gap (ABG) improvement, and operative time. Secondary outcomes were the rate of need for canalplasty, the proportion of self-rated excellent cosmetic results, and pain visual analog scale (VAS).
Forty-three studies enrolled a total of 3712 patients who were undergoing type I tympanoplasty and were finally included. The pooled result showed endoscopic approach was significantly associated with shorter operative time (difference in means: -20.021, 95% confidence interval [CI]: -31.431 to -8.611), less need for canalplasty (odds ratio [OR]: 0.065, 95% CI: 0.026-0.164), more self-rated excellent cosmetic results (OR: 87.323, 95% CI: 26.750-285.063), and lower pain VAS (difference in means: -2.513, 95% CI: -4.737 to -0.228). No significant differences in graft success rate or ABG were observed between the two procedures.
Endoscopic type I tympanoplasty provides a similar graft success rate, improvement in ABG, and reperforation rate to microscopic tympanoplasty with a shorter operative time, better self-rated cosmetic results, and less pain. Unless contraindicated, the endoscopic approach should be the procedure of choice in type I tympanoplasty.
本研究旨在进行系统评价和荟萃分析,比较内镜下和显微镜下 I 型鼓室成形术的临床效果。
纳入随机对照试验、双臂前瞻性研究和回顾性研究。
检索 Medline、Cochrane、EMBASE 和 Google Scholar 数据库,检索时间截至 2022 年 3 月 1 日,使用的检索词组合为“endoscopic”、“microscopic”和“tympanoplasty”。
两名独立的评审员利用上述检索策略确定符合条件的研究。如果对纳入的标准有任何疑问,则咨询第三名评审员。主要结局指标是移植物成功率、气骨导间隙(ABG)改善和手术时间。次要结局指标是需要鼓室成形术的比例、自我评定优秀美容效果的比例和疼痛视觉模拟量表(VAS)评分。
共 43 项研究纳入了 3712 例接受 I 型鼓室成形术的患者,最终纳入 43 项研究。汇总结果显示,内镜下手术与更短的手术时间显著相关(平均差值:-20.021,95%置信区间[CI]:-31.431 至-8.611),更少的需要鼓室成形术(比值比[OR]:0.065,95%CI:0.026-0.164),更高的自我评定优秀美容效果比例(OR:87.323,95%CI:26.750-285.063)和更低的疼痛 VAS 评分(平均差值:-2.513,95%CI:-4.737 至-0.228)。两种手术方法在移植物成功率或 ABG 方面无显著差异。
与显微镜下 I 型鼓室成形术相比,内镜下 I 型鼓室成形术具有相似的移植物成功率、ABG 改善率和再穿孔率,但手术时间更短,自我评定的美容效果更好,疼痛程度更低。除非有禁忌症,否则内镜下手术应作为 I 型鼓室成形术的首选方法。