Shiraishi H, Yanagisawa M
Br Heart J. 1987 Feb;57(2):161-7. doi: 10.1136/hrt.57.2.161.
Pulsed Doppler echocardiograms were obtained from 42 normal fullterm neonates at less than 12 hours (20 subjects), 4 days (20 subjects), and 33 days (12 subjects). The acceleration time of the flow velocity and ventricular systolic time intervals were measured on recordings obtained at the right and left ventricular outflow tract, and the patency of the ductus arteriosus was evaluated by the flow at the pulmonary end of the ductus. The flow velocity pattern of the right ventricular outflow tract changed from a triangular shape with a peak velocity in early systole in the younger age groups to a dome-like contour with a peak velocity in mid-systole; thus the ratio of mean acceleration time to right ventricular ejection time increased with age. The flow velocity pattern of the left ventricular outflow tract was triangular in all age groups, and the ratio of mean acceleration time to left ventricular ejection time showed no significant change with age. The right ventricular pre-ejection period shortened and the right ventricular ejection time lengthened with age; thus the ratio of mean right ventricular pre-ejection period to right ventricular ejection time decreased with age. The left ventricular systolic time intervals showed no significant change with age. The ductus arteriosus was patent in all subjects who were less than 12 hours old but was closed in the older neonates. Pulsed Doppler echocardiography is a valuable method of evaluating pulmonary vascular bed in the early neonatal period.
对42名正常足月新生儿进行了脉冲多普勒超声心动图检查，这些新生儿出生时间分别为不到12小时（20名受试者）、4天（20名受试者）和33天（12名受试者）。在左右心室流出道的记录上测量血流速度的加速时间和心室收缩时间间隔，并通过动脉导管肺端的血流评估动脉导管的通畅情况。右心室流出道的血流速度模式在较年轻年龄组中从早期收缩期峰值速度呈三角形，转变为中期收缩期峰值速度呈圆顶状；因此，平均加速时间与右心室射血时间的比值随年龄增加。左心室流出道的血流速度模式在所有年龄组中均为三角形，平均加速时间与左心室射血时间的比值随年龄无显著变化。右心室射血前期随年龄缩短，右心室射血时间随年龄延长；因此，平均右心室射血前期与右心室射血时间的比值随年龄降低。左心室收缩时间间隔随年龄无显著变化。动脉导管在所有出生不到12小时的受试者中均通畅，但在较大的新生儿中已闭合。脉冲多普勒超声心动图是评估新生儿早期肺血管床的一种有价值的方法。
