UNC School of Medicine, Chapel Hill, NC, USA.
Duke University School of Medicine, Durham, NC, USA.
J Perioper Pract. 2024 Nov;34(11):363-368. doi: 10.1177/17504589231215932. Epub 2023 Dec 27.
Hypotension following induction of general anaesthesia has been shown to result in increased complications and mortality postoperatively. Patients admitted to the hospital undergoing urgent surgery are often fasted from fluids for significant periods compared to elective patients subject to Enhanced Recovery After Surgery protocols despite guidelines stating that a two-hour fast is sufficient. The aim of this prospective, observational study was to compare fasting times and intravascular volume status between elective surgery patients subject to enhanced recovery protocols and inpatient, urgent surgery patients and to assess differences in the incidence of post-induction hypotension. Fasting data was obtained by questionnaire in the preoperative area in addition to inferior vena cava collapsibility index, a non-invasive measure of intravascular volume. Blood pressure readings and drug administration for the ten minutes following induction were obtained from patients' charts. Inpatients undergoing urgent surgery were fasted significantly longer than enhanced recovery patients and had lower intravascular volume. However, no difference was found in the incidence of post-induction hypotension.
全麻诱导后出现低血压已被证明会增加术后并发症和死亡率。与接受强化康复后手术方案的择期手术患者相比,住院接受紧急手术的患者在术前通常需要禁食很长时间,尽管指南指出禁食两小时就足够了。本前瞻性观察研究的目的是比较接受强化康复方案的择期手术患者与住院、紧急手术患者之间的禁食时间和血管内容量状态,并评估诱导后低血压发生率的差异。除下腔静脉塌陷指数(一种非侵入性血管内容量测量方法)外,还通过术前区域的问卷调查获得禁食数据。从患者的图表中获得诱导后十分钟的血压读数和药物治疗。住院接受紧急手术的患者禁食时间明显长于接受强化康复治疗的患者,且血管内容量较低。然而,诱导后低血压的发生率没有差异。