Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA.
Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA.
Gerontologist. 2024 Jun 1;64(6). doi: 10.1093/geront/gnad173.
Social disconnection is highly prevalent in older adults and is associated with frailty. It is unclear which aspects of social disconnection are most associated with frailty, which ones are difference-making, and which combination of social factors are directly linked to frailty.
We conducted a secondary coincidence analysis (CNA) of 1,071 older adults from the Rush Memory and Aging Project (mean age 79.3 ± 7.1; 75.8% female) to identify combinations of social factors that are difference-making for frailty. We included 7 demographic (e.g., age, sex, socioeconomic status) and structural (e.g., social network), functional (e.g., social support, social activity), and quality (e.g., loneliness) aspects of social connection. An established cut score of 0.2 on a frailty index was used to define frailty as the outcome.
CNA produced 46 solution models for the presence of frailty in the data set. The top-scoring model was underfit, leaving a final complex solution path for frailty with the highest fit-robustness score that met the fit parameter cutoffs. We found that the combination of loneliness, low social activity, and older age was present 82% of the time when frailty was present.
The combination of loneliness, social activity, and old age is difference-making for frailty, and supports the inclusion of social factors in frailty prevention and intervention. Further research is needed in diverse data sets to better understand the interrelationships between the 3 aspects of social connection and frailty.
社会隔离在老年人中非常普遍,与虚弱有关。目前尚不清楚社会隔离的哪些方面与虚弱关系最密切,哪些方面起决定作用,以及哪些社会因素组合与虚弱直接相关。
我们对 Rush 记忆与衰老项目中的 1071 名老年人(平均年龄 79.3±7.1 岁,75.8%为女性)进行了二次巧合分析(CNA),以确定与虚弱有关的社会因素组合。我们纳入了 7 个社会联系的人口统计学(如年龄、性别、社会经济地位)和结构性(如社交网络)、功能性(如社会支持、社会活动)和质量(如孤独)方面。采用已建立的虚弱指数得分 0.2 作为虚弱的判定标准。
CNA 为数据集的虚弱状态产生了 46 个解决方案模型。得分最高的模型拟合不足,留下了最终的复杂解决方案路径,用于虚弱的拟合稳健性评分最高,符合拟合参数的截止值。我们发现,当存在虚弱时,孤独、低社会活动和年龄较大的组合出现的概率为 82%。
孤独、社会活动和年龄的组合对虚弱有决定作用,支持在虚弱预防和干预中纳入社会因素。需要在不同的数据集进行进一步研究,以更好地理解社会联系的 3 个方面与虚弱之间的相互关系。