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一名老年男性的心动过缓、肾衰竭、房室传导阻滞、休克和高钾血症(BRASH)综合征病例及其处理:病例报告与文献综述

A Case of Bradycardia, Renal Failure, Atrioventricular Nodal Blockade, Shock, and Hyperkalaemia (BRASH) Syndrome in an Elderly Male and Its Management: A Case Report and Literature Review.

作者信息

Hussain Akbar, Ahmed Nazneen, Marlowe Stanley, Piercy Jonathan, Kommineni Sai S

机构信息

Internal Medicine, Appalachian Regional Healthcare, Harlan, USA.

出版信息

Cureus. 2023 Nov 27;15(11):e49489. doi: 10.7759/cureus.49489. eCollection 2023 Nov.

Abstract

BRASH syndrome, characterized by bradycardia, renal dysfunction, atrioventricular (AV) nodal blockage, shock, and hyperkalemia, is a rare but potentially life-threatening condition resulting from the interplay between AV nodal blockers and hyperkalemia. This complex syndrome poses significant challenges in diagnosis and management, with patients often presenting with bradycardia and high potassium levels. This case report highlights the need for increased awareness of BRASH syndrome, especially in an aging population and evolving cardiovascular treatments. Early recognition and a comprehensive, multidisciplinary approach are crucial for improving outcomes in affected patients.

摘要

BRASH综合征以心动过缓、肾功能不全、房室结阻滞、休克和高钾血症为特征,是一种由房室结阻滞剂和高钾血症相互作用导致的罕见但可能危及生命的疾病。这种复杂的综合征在诊断和管理方面带来了重大挑战,患者常表现为心动过缓和高钾血症。本病例报告强调了提高对BRASH综合征认识的必要性,尤其是在老龄化人群和不断发展的心血管治疗背景下。早期识别和全面的多学科方法对于改善受影响患者的预后至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8168/10751601/117e4eae0eb6/cureus-0015-00000049489-i01.jpg

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本文引用的文献

1
BRASH syndrome - fact or fiction? A first analysis of the prevalence and relevance of a newly described syndrome.
Eur J Emerg Med. 2021 Apr 1;28(2):153-155. doi: 10.1097/MEJ.0000000000000762.
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BRASH Syndrome with Hyperkalemia: An Under-Recognized Clinical Condition.
Methodist Debakey Cardiovasc J. 2020 Jul-Sep;16(3):241-244. doi: 10.14797/mdcj-16-3-241.
3
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J Emerg Med. 2020 Aug;59(2):216-223. doi: 10.1016/j.jemermed.2020.05.001. Epub 2020 Jun 18.
4
BRASH syndrome.
BMJ Case Rep. 2020 Feb 23;13(2):e233825. doi: 10.1136/bcr-2019-233825.
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Trimethoprim/Sulfamethoxazole-Induced Bradycardia, Renal Failure, AV-Node Blockers, Shock and Hyperkalemia Syndrome.
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