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以心动过缓、肾衰竭、房室传导阻滞、休克和高钾血症(BRASH)综合征为表现的转甲状腺素蛋白心脏淀粉样变性:一例报告

Transthyretin Cardiac Amyloidosis Presenting as Bradycardia, Renal Failure, Atrioventricular-Nodal Blockade, Shock, and Hyperkalemia (BRASH) Syndrome: A Case Report.

作者信息

Khatun Nazima, Brown Bernard, Francois Jonathan, Budzikowski Adam S, Salciccioli Louis, John Sabu

机构信息

Department of Internal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.

Department of Cardiology, State University of New York Downstate Medical Center, Brooklyn, USA.

出版信息

Cureus. 2023 Sep 1;15(9):e44532. doi: 10.7759/cureus.44532. eCollection 2023 Sep.

Abstract

BRASH syndrome involves the chain of events resulting from the collective effects of radycardia, enal failure, trioventricular (AV)-nodal blockade, hock, and yperkalemia. BRASH syndrome can rapidly progress to cardiac arrest. Early recognition is crucial. We present a case of transthyretin cardiac amyloidosis (ATTR-CA) in an elderly woman who presented with BRASH syndrome shortly after an AV-nodal blocker was prescribed for atrial fibrillation.

摘要

BRASH综合征涉及由心动过缓、肾衰竭、房室结阻滞、休克和高钾血症的共同作用所引发的一系列事件。BRASH综合征可迅速进展为心脏骤停。早期识别至关重要。我们报告一例老年女性转甲状腺素蛋白心脏淀粉样变(ATTR-CA)病例,该患者在因心房颤动开具房室结阻滞剂后不久出现BRASH综合征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c05e/10544653/cac2e74c5c25/cureus-0015-00000044532-i01.jpg

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