School of Kinesiology and Nutrition, University of Southern Mississippi, 118 College Drive, Hattiesburg, MS, USA.
Eur J Appl Physiol. 2024 May;124(5):1547-1559. doi: 10.1007/s00421-023-05390-2. Epub 2023 Dec 29.
This study tested the hypothesis that blood pressure responses would increase relative to force production in response to prolonged bouts of muscular work.
Fifteen individuals performed two minutes of static handgrip (SHG; 35% MVC), followed by three minutes of post-exercise-cuff-occlusion (PECO), before and after thirty minutes of rest (control), or rhythmic handgrip exercise (RHG) of the contralateral and ipsilateral forearms. Beat-by-beat recordings of mean arterial pressure (MAP), heart rate (HR), and handgrip force (kg) were averaged across one-minute periods at baseline, and minutes 5, 10, 15, 20, 25, and 30 of RHG. MAP was also normalized to handgrip force, providing a relative measure of exercise pressor responses (mmHg/kg). Hemodynamic responses to SHG and PECO were also compared before and after contralateral RHG, ipsilateral RHG, and control, respectively. Similar to the RHG trial, areas under the curve were calculated for MAP (blood pressure index; BPI) and normalized to the time tension index (BPI).
HR and MAP significantly increased during RHG (15.3 ± 1.4% and 20.4 ± 3.2%, respectively, both p < 0.01), while force output decreased by up to 36.6 ± 8.0% (p < 0.01). This resulted in a 51.6 ± 9.4% increase in BPI during 30 min of RHG (p < 0.01). In contrast, blood pressure responses to SHG and PECO were unchanged following RHG (all p ≥ 0.07), and only the mean HR (4.2 ± 1.5%, p = 0.01) and ΔHR (67.2 ± 18.1%, p < 0.01) response to SHG were exaggerated following ipsilateral RHG.
The magnitude of exercise pressor responses relative to force production progressively increases during, but not following, prolonged bouts of muscular work.
本研究旨在验证以下假设，即在长时间的肌肉工作后，血压反应相对于力量产生会增加。
15 名个体分别进行两分钟的静态握力（SHG；35%最大握力），然后进行三分钟的运动后袖口加压（PECO），分别在休息 30 分钟（对照）前后，或对侧和同侧前臂进行节律性握力运动（RHG）。在基线、RHG 的第 5、10、15、20、25 和 30 分钟，每一分钟平均记录平均动脉压（MAP）、心率（HR）和握力（kg）的逐拍记录。MAP 也按握力进行标准化，提供运动加压反应的相对测量值（mmHg/kg）。还分别比较了 SHG 和 PECO 在前、后对侧 RHG、同侧 RHG 和对照后的血液动力学反应。与 RHG 试验类似，还计算了 MAP（血压指数；BPI）和标准化时间张力指数（BPI）的曲线下面积。
在 RHG 期间，HR 和 MAP 显著增加（分别增加 15.3±1.4%和 20.4±3.2%，均 p<0.01），而力量输出下降了高达 36.6±8.0%（p<0.01）。这导致在 30 分钟的 RHG 期间，BPI 增加了 51.6±9.4%（p<0.01）。相比之下，在 RHG 之后，SHG 和 PECO 的血压反应没有变化（均 p≥0.07），只有 SHG 的平均 HR（4.2±1.5%，p=0.01）和 ΔHR（67.2±18.1%，p<0.01）反应在同侧 RHG 后被夸大。
在长时间的肌肉工作期间，但不在之后，相对于力量产生，运动加压反应的幅度逐渐增加。
