Miyamoto Nobukazu, Ueno Yuji, Yamashiro Kazuo, Hira Kenichiro, Kijima Chikage, Kitora Naoki, Iwao Yoshihiko, Okuda Kayo, Mishima Shohei, Takahashi Daisuke, Ono Kazuto, Asari Mika, Miyazaki Kazuki, Hattori Nobutaka
Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
HACARUS INC., Kyoto, Japan.
Front Neurol. 2023 Dec 14;14:1295642. doi: 10.3389/fneur.2023.1295642. eCollection 2023.
It is important to diagnose cerebral infarction at an early stage and select an appropriate treatment method. The number of stroke-trained physicians is unevenly distributed; thus, a shortage of specialists is a major problem in some regions. In this retrospective design study, we tested whether an artificial intelligence (AI) we built using computer-aided detection/diagnosis may help medical physicians to classify stroke for the appropriate treatment.
To build the Stroke Classification and Treatment Support System AI, the clinical data of 231 hospitalized patients with ischemic stroke from January 2016 to December 2017 were used for training the AI. To verify the diagnostic accuracy, 151 patients who were admitted for stroke between January 2018 and December 2018 were also enrolled.
By utilizing multimodal data, such as DWI and ADC map images, as well as patient examination data, we were able to construct an AI that can explain the analysis results with a small amount of training data. Furthermore, the AI was able to classify with high accuracy (Cohort 1, evaluation data 88.7%; Cohort 2, validation data 86.1%).
In recent years, the treatment options for cerebral infarction have increased in number and complexity, making it even more important to provide appropriate treatment according to the initial diagnosis. This system could be used for initial treatment to automatically diagnose and classify strokes in hospitals where stroke-trained physicians are not available and improve the prognosis of cerebral infarction.
早期诊断脑梗死并选择合适的治疗方法至关重要。接受过卒中培训的医生数量分布不均;因此,专家短缺在一些地区是一个主要问题。在这项回顾性设计研究中,我们测试了我们使用计算机辅助检测/诊断构建的人工智能(AI)是否可以帮助医生对卒中进行分类以选择合适的治疗方法。
为构建卒中分类与治疗支持系统人工智能,我们使用了2016年1月至2017年12月期间231例住院缺血性卒中患者的临床数据来训练该人工智能。为验证诊断准确性,我们还纳入了2018年1月至2018年12月期间因卒中入院的151例患者。
通过利用多模态数据,如弥散加权成像(DWI)和表观扩散系数(ADC)图图像以及患者检查数据,我们能够构建一个仅用少量训练数据就能解释分析结果的人工智能。此外,该人工智能能够进行高精度分类(队列1,评估数据为88.7%;队列2,验证数据为86.1%)。
近年来,脑梗死的治疗选择在数量和复杂性上都有所增加,根据初始诊断提供适当的治疗变得更加重要。该系统可用于初始治疗,在没有接受过卒中培训医生的医院中自动诊断和分类卒中,并改善脑梗死的预后。