Gao Yunan, Wang Rui, Liu Qiong, Zhou Bo, Qiao Hu
Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Respiratory and Critical Care Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Heliyon. 2023 Dec 3;10(1):e23292. doi: 10.1016/j.heliyon.2023.e23292. eCollection 2024 Jan 15.
Patients may have uncomfortable feelings during orthodontic treatment, which can directly lead to dissatisfaction. So in order to improve the patient's sense of pleasure during the treatment, it would be of great benefit if orthodontic pain can be relieved.
We included 150 patients wearing clear aligners from 18 to 30 years old during 2018-2020. Then designed following groups to determine the effectiveness of both verbal behavior modification and combination therapy with acetaminophen in reducing treatment pain: Group A, generalized anxiety disorder 7 (GAD-7) scored 0-4; Group B, GAD-7 scored 5-9; Group C, GAD-7 scored 10-14; and Group D, GAD-7 scored 15-21.
There was a difference in the visual analog scale (VAS) between verbal behavior modification with and without a 300-mg acetaminophen tablet oral QD in Group A (received the intervention at 8 h and 1 d), Group B at 8 h and 1 d, Group C at 8 h, 1 d, 2 d, and 3 d, and Group D at 8 h, 1 d, 2 d, 3 d, and 4 d. After 8 h, 1 d, 2 d, 3 d, and 4 d in patients with verbal behavior modification, VAS was markedly increased in Group D compared with Group A, B and C. Furthermore, after 8 h and 1 d in patients with verbal behavior modification and 300-mg acetaminophen tablet oral QD, VAS was strongly enhanced in Group D.
Dental anxiety is strongly associated with pain in orthodontic patients receiving clear aligners. Acetaminophen administration may be a benefit in orthodontic pain that results from clear aligners, especially in the group with more GAD-7.
正畸治疗期间患者可能会有不适感，这会直接导致不满。因此，为了提高患者在治疗期间的愉悦感，缓解正畸疼痛将大有裨益。
我们纳入了2018年至2020年期间150名年龄在18至30岁佩戴透明矫治器的患者。然后设计以下几组来确定言语行为修正和对乙酰氨基酚联合治疗在减轻治疗疼痛方面的有效性：A组，广泛性焦虑障碍量表（GAD-7）评分为0-4；B组，GAD-7评分为5-9；C组，GAD-7评分为10-14；D组，GAD-7评分为15-21。
A组（在8小时和1天时接受干预）、B组在8小时和1天时、C组在8小时、1天、2天和3天时、D组在8小时、1天、2天、3天和4天时，使用和不使用每日口服一次300毫克对乙酰氨基酚片的言语行为修正之间，视觉模拟量表（VAS）存在差异。在进行言语行为修正的患者中，8小时、1天、2天、3天和4天后，与A、B、C组相比，D组的VAS显著增加。此外，在进行言语行为修正并每日口服一次300毫克对乙酰氨基酚片的患者中，8小时和1天后，D组的VAS明显增强。
牙科焦虑与接受透明矫治器的正畸患者的疼痛密切相关。服用对乙酰氨基酚可能有助于缓解透明矫治器引起的正畸疼痛，尤其是在GAD-7评分较高的组中。
