一项评价口头行为矫正和对乙酰氨基酚在正畸疼痛中有效性的随机、单盲、安慰剂对照试验。
A randomized, single-blind, placebo-controlled trial to evaluate the effectiveness of verbal behavior modification and acetaminophen on orthodontic pain.
出版信息
Angle Orthod. 2019 Jul;89(4):617-623. doi: 10.2319/080518-570.1. Epub 2019 Feb 12.
OBJECTIVES
To evaluate the effectiveness of verbal behavior modification, acetaminophen, and the combined effectiveness of verbal behavior modification along with acetaminophen on orthodontic pain.
MATERIALS AND METHODS
One hundred and forty orthodontic fixed appliance patients were randomly assigned to four groups. Group A was administered acetaminophen, group B was given verbal behavior modification, group C was administered acetaminophen as well as verbal behavior modification, and group D was placebo-controlled. A visual analog scale was used to assess pain intensity after 1 week of separator placement.
RESULTS
Group A had less mean pain intensity when compared to group B at 6 hours ( < .001) and at 1 ( < .001) and 2 ( = .002) days. Group C patients encountered less mean pain intensity when compared to group B patients at 6 hours ( < .001) and at 1 ( < .001), 2 ( < .001), and 4 ( = .001) days. There was a statistically significant difference between groups A and C (group C experienced less pain intensity) after 6 hours ( = .004) and at day 4 ( = .009) after separator placement.
CONCLUSIONS
Acetaminophen is the main agent of orthodontic pain reduction after separator placement, with verbal behavior serving as an adjunct to it.
目的
评估口头行为矫正、对乙酰氨基酚以及口头行为矫正联合对乙酰氨基酚在正畸疼痛管理中的有效性。
材料与方法
将 140 名接受固定正畸治疗的患者随机分为 4 组。A 组给予对乙酰氨基酚，B 组给予口头行为矫正，C 组给予对乙酰氨基酚和口头行为矫正，D 组给予安慰剂对照。使用视觉模拟评分法在分离体放置后 1 周评估疼痛强度。
结果
与 B 组相比，A 组在 6 小时（<0.001）、1 天（<0.001）和 2 天（=0.002）时的平均疼痛强度较低。与 B 组相比，C 组在 6 小时（<0.001）、1 天（<0.001）、2 天（<0.001）和 4 天（=0.001）时的平均疼痛强度较低。在分离体放置后 6 小时（=0.004）和第 4 天（=0.009），A 组和 C 组之间存在统计学显著差异（C 组疼痛强度较低）。
结论
对乙酰氨基酚是分离体放置后减轻正畸疼痛的主要药物，口头行为矫正作为其辅助手段。
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