Strahlenklinik, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Klinik für Radiologie-Medizinphysik, Universitätsklinikum Freiburg, Freiburg, Germany.
Strahlenther Onkol. 2024 Jan;200(1):1-18. doi: 10.1007/s00066-023-02183-6. Epub 2024 Jan 2.
Accurate Magnetic Resonance Imaging (MRI) simulation is fundamental for high-precision stereotactic radiosurgery and fractionated stereotactic radiotherapy, collectively referred to as stereotactic radiotherapy (SRT), to deliver doses of high biological effectiveness to well-defined cranial targets. Multiple MRI hardware related factors as well as scanner configuration and sequence protocol parameters can affect the imaging accuracy and need to be optimized for the special purpose of radiotherapy treatment planning. MRI simulation for SRT is possible for different organizational environments including patient referral for imaging as well as dedicated MRI simulation in the radiotherapy department but require radiotherapy-optimized MRI protocols and defined quality standards to ensure geometrically accurate images that form an impeccable foundation for treatment planning. For this guideline, an interdisciplinary panel including experts from the working group for radiosurgery and stereotactic radiotherapy of the German Society for Radiation Oncology (DEGRO), the working group for physics and technology in stereotactic radiotherapy of the German Society for Medical Physics (DGMP), the German Society of Neurosurgery (DGNC), the German Society of Neuroradiology (DGNR) and the German Chapter of the International Society for Magnetic Resonance in Medicine (DS-ISMRM) have defined minimum MRI quality requirements as well as advanced MRI simulation options for cranial SRT.
准确的磁共振成像(MRI)模拟对于高精度立体定向放射外科和分次立体定向放疗(SRT)至关重要,SRT 是指将高生物学效应的剂量精确输送到明确定义的颅靶区。多种与 MRI 硬件相关的因素,以及扫描器配置和序列协议参数,都可能影响成像准确性,需要针对放射治疗计划的特殊目的进行优化。SRT 的 MRI 模拟可在不同的组织环境下进行,包括为成像而进行的患者转介,以及在放射治疗部门进行专门的 MRI 模拟,但需要放射治疗优化的 MRI 协议和定义的质量标准,以确保具有精确几何形状的图像,为治疗计划奠定坚实基础。为制定本指南,一个由德国放射肿瘤学会(DEGRO)的放射外科和立体定向放疗工作组、德国医学物理学会(DGMP)的立体定向放疗物理和技术工作组、德国神经外科学会(DGNC)、德国神经放射学会(DGNR)以及国际磁共振医学学会(ISMRM)德国分会的专家组成的跨学科小组,为颅 SRT 定义了最低 MRI 质量要求以及先进的 MRI 模拟选项。