Balitskaia E K, Shmal'ko Iu P
Eksp Onkol. 1987;9(1):71-4.
The effect of cyclophosphamide and 5-fluorouracil on the neurochemical determinants of the functional state of the sympatho-adrenal system (SAS) is studied in C57BL mice with metastatic Lewis carcinoma and tumours induced by subcutaneous administration of 20-methylcholanthrene. It is established that pathologic effect of cytostatics on the SAS is especially pronounced at the late stages of the tumour process. In this case urine excretion of DOPA, catecholamines and their catabolites is observed.
研究了环磷酰胺和5-氟尿嘧啶对携带转移性Lewis癌的C57BL小鼠以及皮下注射20-甲基胆蒽诱导的肿瘤小鼠交感-肾上腺系统（SAS）功能状态的神经化学决定因素的影响。已确定细胞抑制剂对SAS的病理作用在肿瘤进程的晚期尤为明显。在这种情况下，观察到了多巴、儿茶酚胺及其代谢产物的尿排泄。
