Department of Psychiatry & Behavioral Sciences, University of Minnesota, 2025 E River Parkway, 55414, Minneapolis, MN, USA.
Department of Psychology, University of Minnesota, Minneapolis, MN, USA.
BMC Med Inform Decis Mak. 2024 Jan 2;24(1):4. doi: 10.1186/s12911-023-02410-1.
Machine learning based clinical decision support systems (CDSSs) have been proposed as a means of advancing personalized treatment planning for disorders, such as depression, that have a multifaceted etiology, course, and symptom profile. However, machine learning based models for treatment selection are rare in the field of psychiatry. They have also not yet been translated for use in clinical practice. Understanding key stakeholder attitudes toward machine learning based CDSSs is critical for developing plans for their implementation that promote uptake by both providers and families.
In Study 1, a prototype machine learning based Clinical Decision Support System for Youth Depression (CDSS-YD) was demonstrated to focus groups of adolescents with a diagnosis of depression (n = 9), parents (n = 11), and behavioral health providers (n = 8). Qualitative analysis was used to assess their attitudes towards the CDSS-YD. In Study 2, behavioral health providers were trained in the use of the CDSS-YD and they utilized the CDSS-YD in a clinical encounter with 6 adolescents and their parents as part of their treatment planning discussion. Following the appointment, providers, parents, and adolescents completed a survey about their attitudes regarding the use of the CDSS-YD.
All stakeholder groups viewed the CDSS-YD as an easy to understand and useful tool for making personalized treatment decisions, and families and providers were able to successfully use the CDSS-YD in clinical encounters. Parents and adolescents viewed their providers as having a critical role in the use the CDSS-YD, and this had implications for the perceived trustworthiness of the CDSS-YD. Providers reported that clinic productivity metrics would be the primary barrier to CDSS-YD implementation, with the creation of protected time for training, preparation, and use as a key facilitator.
Machine learning based CDSSs, if proven effective, have the potential to be widely accepted tools for personalized treatment planning. Successful implementation will require addressing the system-level barrier of having sufficient time and energy to integrate it into practice.
基于机器学习的临床决策支持系统 (CDSS) 已被提议作为推进具有多方面病因、病程和症状特征的疾病(如抑郁症)个性化治疗计划的一种手段。然而,在精神病学领域,用于治疗选择的基于机器学习的模型很少。它们也尚未被翻译用于临床实践。了解关键利益相关者对基于机器学习的 CDSS 的态度对于制定实施计划至关重要,这些计划可以促进提供者和家庭接受它们。
在研究 1 中,向一组患有抑郁症诊断的青少年(n=9)、父母(n=11)和行为健康提供者(n=8)的焦点小组展示了一个基于机器学习的青少年抑郁症临床决策支持系统 (CDSS-YD) 的原型。使用定性分析来评估他们对 CDSS-YD 的态度。在研究 2 中,行为健康提供者接受了使用 CDSS-YD 的培训,并在与 6 名青少年及其父母的临床预约中使用 CDSS-YD 作为他们治疗计划讨论的一部分。预约结束后,提供者、父母和青少年完成了一份关于他们对使用 CDSS-YD 的态度的调查。
所有利益相关者群体都认为 CDSS-YD 是一个易于理解和有用的个性化治疗决策工具,并且家庭和提供者能够在临床会议中成功使用 CDSS-YD。父母和青少年认为他们的提供者在使用 CDSS-YD 方面发挥着关键作用,这对 CDSS-YD 的可信赖性产生了影响。提供者报告说,诊所生产力指标将是 CDSS-YD 实施的主要障碍,而创建受保护的时间进行培训、准备和使用是一个关键的促进因素。
如果基于机器学习的 CDSS 被证明有效,它们有可能成为个性化治疗计划的广泛接受的工具。成功实施将需要解决系统层面的障碍,即有足够的时间和精力将其整合到实践中。