Belmont University College of Pharmacy, Nashville, TN, 37212, USA.
Division of Clinical Informatics, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.
Syst Rev. 2024 Jan 2;13(1):12. doi: 10.1186/s13643-023-02413-z.
Patient misunderstanding of instructions on medication labels is a common cause of medication errors and can result in ineffective treatment. One way to better improve patient comprehension of medication labels is by optimizing the content and display of the information.
To review comparative studies that have evaluated the design of a medication label to improve patient knowledge or safety.
Studies were selected from systematic computerized literature searches performed in PubMed, Embase (Elsevier), Cochrane Central (EBSCO), Cumulative Index to Nursing and Allied Health Literature-CINAHL (EBSCO), and Web of Science (Thomson Reuters). Eligible studies included comparative studies that evaluated the design of a medication label to improve patient knowledge or safety.
Of the 246 articles identified in the primary literature search, 14 studies were selected for data abstraction. Thirteen of these studies significantly impacted the patient understanding of medication labels. Three studies included a measure of patient safety in terms of medication adherence and dosing errors. The utilization of patient-centered language, pictograms/graphics, color/white space, or font optimization was seen to have the most impact on patient comprehension.
It is essential to present medication information in an optimal manner for patients. This can be done by standardizing the content, display, and format of medication labels to improve understanding and medication usage. Evidence-based design principles can, therefore, be used to facilitate the standardization of the structure of label content for both print and electronic devices. However, more research needs to be done on validating the implications of label content display to measure its impact on patient safety.
PROSPERO CRD42022347510 ( http://www.crd.york.ac.uk/prospero/ ).
患者对药物标签上的用药说明理解有误，是导致用药错误的常见原因，可能会使治疗无效。改善患者对药物标签理解的一种方法是优化信息的内容和呈现方式。
综述评估药物标签设计以提高患者知识或安全性的对比研究。
从 PubMed、Embase（Elsevier）、Cochrane Central（EBSCO）、Cumulative Index to Nursing and Allied Health Literature-CINAHL（EBSCO）和 Web of Science（Thomson Reuters）中进行了系统的计算机文献检索，筛选出评估药物标签设计以提高患者知识或安全性的对比研究。符合条件的研究包括评估药物标签设计以提高患者知识或安全性的对比研究。
在初步文献检索中确定的 246 篇文章中，有 14 篇文章被选中进行数据提取。其中 13 项研究显著影响了患者对药物标签的理解。有 3 项研究从药物依从性和剂量错误方面衡量了患者安全。使用以患者为中心的语言、象形图/图形、颜色/空白或字体优化，对患者理解的影响最大。
以最佳方式向患者呈现药物信息至关重要。可以通过标准化药物标签的内容、呈现和格式来实现这一点，以提高理解和药物使用。因此，可以利用基于证据的设计原则来促进标签内容结构的标准化，包括印刷和电子设备。然而，需要进一步研究验证标签内容显示对患者安全的影响。
PROSPERO CRD42022347510（http://www.crd.york.ac.uk/prospero/）。
