Klöppel G, Knöfel W T, Baisch H, Otto U
Eur Urol. 1986;12(6):426-31. doi: 10.1159/000472673.
In 135 renal cell carcinomas (RCCs), nuclear grade, Robson stage and DNA content, determined by flow cytometry, were related to the 3-year survival rates of the respective patients. All three parameters showed prognostic value, nuclear grading being most effective. Combined evaluation of the parameters showed that staging and also DNA determination add supplementary prognostic information. As the four nuclear grades clearly uncover the biological potential of RCC, they are regarded as the most significant criteria for the prognostic assessment of RCC.
在135例肾细胞癌（RCC）中，通过流式细胞术测定的核分级、罗布森分期和DNA含量与各患者的3年生存率相关。所有这三个参数均显示出预后价值，其中核分级最为有效。对这些参数进行综合评估表明，分期以及DNA测定可提供补充性的预后信息。由于这四个核分级清楚地揭示了肾细胞癌的生物学潜能，它们被视为肾细胞癌预后评估的最重要标准。
