Obstetrics Department, Zhejiang Hospital, Hangzhou, China.
Int Wound J. 2024 Apr;21(4):e14535. doi: 10.1111/iwj.14535. Epub 2024 Jan 2.
A meta-analysis study was executed to measure the effect of minimally invasive surgery (MIS) and open surgical management (OSM) on wound infection (WI) in female's cervical cancer (CC). A comprehensive literature study till February 2023 was applied and 1675 interrelated investigations were reviewed. The 41 chosen investigations enclosed 10 204 females with CC and were in the chosen investigations' starting point, 4294 of them were utilizing MIS, and 5910 were utilizing OSM. Odds ratio (OR) in addition to 95% confidence intervals (CIs) were utilized to compute the value of the effect of MIS and OSM on WI in female's CC and by the dichotomous approaches and a fixed or random model. The MIS had significantly lower WI (OR, 0.23; 95% CI, 0.15-0.35, p < 0.001) with no heterogeneity (I = 0%) and postoperative aggregate complications (PACs) (OR, 0.49; 95% CI, 0.37-0.64, p < 0.001) in females with CC and compared OSM. However, MIS compared with OSM in females with CC and had no significant difference in pelvic infection and abscess (PIA) (OR, 0.59; 95% CI, 0.31-1.16, p = 0.13). The MIS had significantly lower WI, and PACs, though, had no significant difference in PIA in females with CC and compared with OSM. However, care must be exercised when dealing with its values because of the low sample size of some of the nominated investigations for the meta-analysis.
一项荟萃分析研究旨在衡量微创手术（MIS）和开放式手术管理（OSM）对女性宫颈癌（CC）中伤口感染（WI）的影响。该研究进行了全面的文献综述，截止到 2023 年 2 月，共回顾了 1675 项相关研究。在纳入的 41 项研究中，共有 10204 名女性患有 CC，在研究起点，4294 名女性接受了 MIS，5910 名女性接受了 OSM。采用比值比（OR）和 95%置信区间（CI）来计算 MIS 和 OSM 对女性 CC 中 WI 的影响，采用二项式方法和固定或随机模型。MIS 与 OSM 相比，WI 发生率显著降低（OR，0.23；95%CI，0.15-0.35，p<0.001），且异质性低（I=0%），术后总并发症（PACs）发生率也较低（OR，0.49；95%CI，0.37-0.64，p<0.001）。然而，MIS 与 OSM 相比，女性 CC 中盆腔感染和脓肿（PIA）发生率差异无统计学意义（OR，0.59；95%CI，0.31-1.16，p=0.13）。MIS 与 OSM 相比，WI 和 PACs 发生率较低，但 PIA 发生率差异无统计学意义。然而，由于部分纳入荟萃分析的研究样本量较小，在处理其结果时需要谨慎。
