Song Ran, Ma Mingming, Yang Nana, Chen Chunfang, Wang Huan, Li Juan
Department of Gynecology, Maternal & Child Health Center Of Dezhou, No. 835 Dongdi middle Avenue, Decheng District, Dezhou, China.
BMC Surg. 2024 Dec 23;24(1):413. doi: 10.1186/s12893-024-02713-8.
To evaluate the impact of open surgical care (OSC) compared to minimally invasive surgery (MIS) on the occurrence of wound infection (WI) and overall postoperative aggregate complications (POACs) in female cervical cancer (CC) patients, we conducted this meta-analysis study. A thorough examination of the literature up to March 2024 was conducted, and 1849 related studies were examined. The 44 studies that were selected included 11,631 females who had CC. The odds ratio (ORs) and the estimation using 95% confidence intervals (CIs) were used to calculate the impact of open surgical management and MIS on WI and POACs in females with CC, using dichotomous methodologies and a random or fixed model. When comparing MIS to open surgical care, there was a substantial decrease in WI (OR, 0.19; 95% CI, 0.13-0.29, p < 0.001) and POACs (OR, 0.49; 95% CI, 0.38-0.62, p < 0.001) in females with CC. On the other hand, among female patients with CC, MIS did not differ significantly from open surgical care in pelvic infection and abscess (PI&A) incidence (OR, 0.59; 95% CI, 0.31-1.16, p = 0.13). When compared to OSC, women with CC who underwent MIS experienced considerably fewer WI and POACs; however, there was no discernible difference in PI&A rates. However, given several of the designated examinations for the meta-analysis had relatively small sample sizes, caution must be used while handling its values.
为了评估开放手术治疗（OSC）与微创手术（MIS）相比，对女性宫颈癌（CC）患者伤口感染（WI）的发生情况及术后总体并发症（POACs）的影响，我们开展了这项荟萃分析研究。我们对截至2024年3月的文献进行了全面检索，共检索到1849项相关研究。最终选取的44项研究纳入了11,631例患有CC的女性患者。采用二分法及随机或固定效应模型，通过计算比值比（ORs）和95%置信区间（CIs）来评估开放手术治疗和MIS对CC女性患者WI及POACs的影响。与开放手术治疗相比，CC女性患者的WI（OR，0.19；95%CI，0.13 - 0.29，p < 0.001）和POACs（OR，0.49；95%CI，0.38 - 0.62，p < 0.001）显著降低。另一方面，在CC女性患者中，MIS与开放手术治疗在盆腔感染及脓肿（PI&A）发生率方面无显著差异（OR，0.59；95%CI，0.31 - 1.16，p = 0.13）。与OSC相比，接受MIS治疗的CC女性患者的WI和POACs明显更少；然而，PI&A发生率无明显差异。不过，鉴于荟萃分析中的一些指定检查样本量相对较小，在处理其结果时必须谨慎。
