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卡介苗疫苗、抗疟药、年龄和性别与 COVID-19 传播和死亡率的关系。

Bacillus Calmette-Guérin vaccine, antimalarial, age and gender relation to COVID-19 spread and mortality.

机构信息

Microbiology and Immunology Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.

Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.

出版信息

Vaccine. 2020 Jul 31;38(35):5564-5568. doi: 10.1016/j.vaccine.2020.06.083. Epub 2020 Jul 3.

DOI:10.1016/j.vaccine.2020.06.083
PMID:32654907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7332946/
Abstract

COVID-19 is affecting different countries all over the world with great variation in infection rate and death ratio. Some reports suggested a relation between the Bacillus Calmette-Guérin (BCG) vaccine and the malaria treatment to the prevention of SARS-CoV-2 infection. Some reports related infant's lower susceptibility to the COVID-19. Some other reports a higher risk in males compared to females in such COVID-19 pandemic. Also, some other reports claimed the possible use of chloroquine and hydroxychloroquine as prophylactic in such a pandemic. The present commentary is to discuss the possible relation between those factors and SARS-CoV-2 infection.

摘要

COVID-19 正在影响世界上不同的国家,其感染率和死亡率差异很大。一些报告表明,卡介苗(BCG)疫苗和疟疾治疗与预防 SARS-CoV-2 感染之间存在关联。一些报告与婴儿对 COVID-19 的较低易感性有关。还有一些报告称,在 COVID-19 大流行期间,男性的风险高于女性。此外,还有一些报告声称氯喹和羟氯喹可能在这种大流行中用作预防药物。本评论旨在讨论这些因素与 SARS-CoV-2 感染之间可能存在的关系。

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