Medina-Rodríguez José Carlos
Department of Education, National Institute of Psychiatry, Mexico City, MEX.
Department of Neurology and Neuropsychiatry, National Institute of Psychiatry, Mexico City, MEX.
Cureus. 2023 Dec 3;15(12):e49855. doi: 10.7759/cureus.49855. eCollection 2023 Dec.
Throughout history, the cerebellum was initially perceived as potentially vestigial until the 19th century. However, subsequent research illuminated its pivotal role in coordination. Over the course of the 20th century, it became predominantly associated with motor functions. Nevertheless, in the latter half of the century, Schmahmann's pioneering research expanded the understanding of the cerebellum to encompass its involvement in cognition and emotions. In light of this evolving background, the primary objective of this paper is to present a clinical case featuring a 60-year-old male with a history of Epstein-Barr virus. This patient underwent a comprehensive neuropsychiatric assessment at a tertiary care hospital, involving thorough clinical, paraclinical, and neuroimaging examinations. The extensive medical findings strongly indicate the presence of a cognitive-affective cerebellar syndrome.
纵观历史,直到19世纪,小脑最初被认为可能是退化的。然而,随后的研究揭示了它在协调方面的关键作用。在20世纪,它主要与运动功能相关联。尽管如此,在20世纪后半叶,施马曼的开创性研究扩展了对小脑的认识,将其参与认知和情感的方面也涵盖在内。鉴于这一不断演变的背景,本文的主要目的是呈现一个临床病例,该病例为一名60岁男性,有EB病毒感染史。该患者在一家三级护理医院接受了全面的神经精神评估,包括全面的临床、辅助临床和神经影像学检查。大量的医学检查结果有力地表明存在认知情感性小脑综合征。