Song Keke, Liu Chenying, Chen Guangbin, Zhao Wenhao, Tian Shufang, Zhou Qian
Henan International Joint Laboratory of Medicinal Plants Utilization, College of Chemistry and Molecular Sciences, Henan University Kaifeng 475000 China.
RSC Adv. 2024 Jan 3;14(2):1207-1215. doi: 10.1039/d3ra07082d. eCollection 2024 Jan 2.
A paper-based ratiometric fluorescent sensing platform has been developed for glucose detection based on a dual-emission fluorescent probe consisting of carbon quantum dots (C QDs) and CdTe QDs. When the two kinds of QDs are mixed, the fluorescence of C QDs is reversibly quenched by CdTe QDs. However, in the presence of glucose, the fluorescence of CdTe QDs is quenched by HO catalyzed by glucose oxidase (GOx), which restores the fluorescence of C QDs. The proposed paper-based ratiometric fluorescent sensing platform exhibited good sensitivity and selectivity towards glucose. The working linear range was 0.1 mM to 50 mM with a limit of detection (LOD) of 0.026 mM. Additionally, the proposed paper-based sensor possesses viability for the determination of glucose in actual urine samples.
基于由碳量子点（CQDs）和碲化镉量子点（CdTe QDs）组成的双发射荧光探针，开发了一种用于葡萄糖检测的纸质比率荧光传感平台。当将这两种量子点混合时，CdTe QDs会使CQDs的荧光发生可逆猝灭。然而，在葡萄糖存在的情况下，葡萄糖氧化酶（GOx）催化产生的过氧化氢会猝灭CdTe QDs的荧光，从而恢复CQDs的荧光。所提出的纸质比率荧光传感平台对葡萄糖表现出良好的灵敏度和选择性。工作线性范围为0.1 mM至50 mM，检测限（LOD）为0.026 mM。此外，所提出的纸质传感器在实际尿液样本中具有测定葡萄糖的可行性。
