Yang Xiaonan, Cui Yahan, Zhao Niao, Wang Shenghui, Yan Hongyuan, Han Dandan
Hebei Key Laboratory of Public Health Safety, School of Life Sciences, College of Public Health, Hebei University, Baoding, 071002, China.
Hebei Key Laboratory of Public Health Safety, School of Life Sciences, College of Public Health, Hebei University, Baoding, 071002, China; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Chemistry and Materials Science, Hebei University, Baoding, 071002, China.
Talanta. 2024 Apr 1;270:125620. doi: 10.1016/j.talanta.2023.125620. Epub 2024 Jan 1.
Efficiently detecting diamide insecticides in environmental water is challenging due to their low concentrations and complex matrix interferences. In this study, we developed ionic liquids (ILs)-incorporated magnetic molecularly imprinted polymers (IL-MMIPs) for the detection of diamide insecticides, capitalizing on the advantages of ILs and quick magnetic separation through surface imprinting. Tetrachlorantraniliprole was used as the template, and a specific IL, 1-vinyl-3-ethylimidazolium hexafluorophosphate ([VEIm][PF]), was employed as the functional monomer. Various synthesis conditions were investigated to optimize adsorption efficiency. The prepared IL-MMIPs were successfully employed as adsorbents in magnetic solid-phase extraction (MSPE) to selectively extract, separate, and quantify three types of diamide insecticides from water samples using HPLC-UV detection. Under optimal conditions, the analytical method achieved low limits of detection (0.69 ng mL, 0.64 ng mL, 0.59 ng mL for cyantraniliprole, chlorantraniliprole and tetrachlorantraniliprole, respectively). The method also displayed a wide linear range (0.003-10 μg mL for cyantraniliprole and chlorantraniliprole, and 0.004-10 μg mL for tetrachlorantraniliprole, respectively) with satisfactory coefficients (R≥0.9996), and low relative standard deviation (RSD≤2.55%). Additionally, extraction recoveries fell within the range of 79.4%-109%. The results clearly demonstrate that IL-MMIPs exhibit exceptional recognition and rebinding capabilities. The developed IL-MMIPs-MSPE-HPLC-UV method is straightforward and rapid, making it suitable for the detection and analysis of three kinds of diamide insecticides in environmental water.
由于环境水中二酰胺类杀虫剂浓度低且基质干扰复杂，有效检测它们具有挑战性。在本研究中，我们开发了掺入离子液体（ILs）的磁性分子印迹聚合物（IL-MMIPs）用于检测二酰胺类杀虫剂，利用了离子液体的优势以及通过表面印迹实现的快速磁分离。以四氯虫酰胺为模板，使用一种特定的离子液体1-乙烯基-3-乙基咪唑六氟磷酸盐（[VEIm][PF]）作为功能单体。研究了各种合成条件以优化吸附效率。制备的IL-MMIPs成功用作磁性固相萃取（MSPE）中的吸附剂，通过高效液相色谱-紫外检测选择性地从水样中提取、分离和定量三种二酰胺类杀虫剂。在最佳条件下，该分析方法实现了低检测限（氰虫酰胺、氯虫酰胺和四氯虫酰胺分别为0.69 ng mL、0.64 ng mL、0.59 ng mL）。该方法还显示出宽线性范围（氰虫酰胺和氯虫酰胺分别为0.003 - 10 μg mL，四氯虫酰胺为0.004 - 10 μg mL），相关系数令人满意（R≥0.9996），相对标准偏差低（RSD≤2.55%）。此外，萃取回收率在79.4% - 109%范围内。结果清楚地表明IL-MMIPs具有出色的识别和再结合能力。所开发的IL-MMIPs-MSPE-HPLC-UV方法简单快速，适用于环境水中三种二酰胺类杀虫剂的检测和分析。
