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伪装成良性皮肤肿物的头皮原发性皮肤黏液癌——病例报告

Primary cutaneous mucinous carcinoma of the scalp masquerading as a benign dermatological mass - A case report.

作者信息

Alnehlaoui Fadi, Elhadidi Nafad Mohamed Lotfy, Fwakhrji Shafik, Shikare Shekhar V, Alhammadi Majid Hassan, Guraya Salman Yousuf

机构信息

Department of Surgery and Surgical Oncology, Oriana Hospital Sharjah, United Arab Emirates.

Zulekha Hospital Sharjah, United Arab Emirates.

出版信息

Int J Surg Case Rep. 2024 Jan;114:109175. doi: 10.1016/j.ijscr.2023.109175. Epub 2023 Dec 20.

Abstract

INTRODUCTION AND IMPORTANCE

Primary cutaneous mucinous carcinoma (PCMC) is a rare low-grade malignant neoplasm derived from the sweat glands. Local recurrence of PCMC occurs frequently, but these lesions rarely metastasize. Due to the absence of classical demographic and clinical characteristics, PCMCs masquerade as sebaceous cyst, lipoma, pilomatrixoma, chalazion, or squamous cell carcinoma. This misdiagnosis frequently leads to incomplete surgical excision which necessitates further surgical therapy for a curative intent.

CASE PRESENTATION

We present a case of PCMC in a 45-year-old woman which presented as a slow- growing and symptomless nodule in the scalp. After clinical evaluation, the patient had a typical surgical excision for a benign-looking lesion. Histological evaluation of the specimen confirmed a localized PCMC in the scalp with involved surgical margins.

CLINICAL DISCUSSION

A thorough oncological assessment by PET-CT scan and radionuclide scintigraphy was performed. Later, a wide local excision using a gamma probe for intra-operative radionuclide localization of the tumor area and sentinel lymph nodes was done.

CONCLUSION

The patient did not have any regional or distant metastases and remained stable at the time of reporting this case.

摘要

引言与重要性

原发性皮肤黏液癌(PCMC)是一种源自汗腺的罕见低度恶性肿瘤。PCMC常出现局部复发,但这些病变很少发生转移。由于缺乏典型的人口统计学和临床特征,PCMC易被误诊为皮脂腺囊肿、脂肪瘤、毛母质瘤、睑板腺囊肿或鳞状细胞癌。这种误诊常常导致手术切除不彻底,因此需要进一步手术治疗以达到治愈目的。

病例介绍

我们报告一例45岁女性的PCMC病例,该病例表现为头皮上一个生长缓慢且无症状的结节。经过临床评估,患者对一个看似良性的病变进行了典型的手术切除。对标本的组织学评估证实头皮存在局限性PCMC,手术切缘受累。

临床讨论

通过PET-CT扫描和放射性核素闪烁扫描进行了全面的肿瘤学评估。随后,使用γ探针进行了广泛的局部切除,以在术中对肿瘤区域和前哨淋巴结进行放射性核素定位。

结论

该患者没有任何区域或远处转移,在报告此病例时病情保持稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d83b/10800677/439ed4fa59d9/gr1.jpg

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