Radwan Ahmed Ibrahim, Saif Ahmed Mohsen Ibrahim, Samir Younan Ramsis, Maged Wael Ali, Gamal Mohamed A
Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Arab J Urol. 2023 May 16;21(4):273-279. doi: 10.1080/2090598X.2023.2211897. eCollection 2023.
The purpose of this study is to compare results, safety and outcome of ultra-mini-percutaneous nephrolithotomy (PCNL) versus stented shock wave lithotripsy (SWL) for the management of renal calculi sized 10-20 mm.
This study was conducted at Urology Department, Faculty of Medicine, Ain Shams University. After meeting inclusion and exclusion criteria, 90 patients were randomized to either ultra-mini-PCNL group or stented SWL group through the closed-envelope technique, with 45 patients in each group. Patient data were collected preoperatively, immediately postoperatively and 2 and 4 weeks postoperatively assessing operative time, hospital stay, complications including haematuria, fever, the need for blood transfusion, residual stones and the need for retreatment.
Stone-free rate (SFR) was higher in the ultra-mini-PCNL group compared to the stented SWL group, with no statistically significant difference with -value = 0.316. As for the need for retreatment, it was slightly higher in the stented SWL group compared to the ultra-mini-PCNL group, yet this difference was statistically insignificant with -value = 0.681.We found no statistically significant difference between both groups regarding post-operative complications including fever, haematuria and need for blood transfusion, respectively.Operative time and hospital stay were significantly higher in the ultra-mini-PCNL group compared to the stented SWL group with -value < 0.001 for both.
Both stented SWL and ultra-mini-PCNL are good treatment choices for renal stones sized less than 2 cm with low complication rates. Stone size indices were significant predictor for the need for retreatment. Further studies to compare SFR based on stone size in both interventions are needed.
本研究旨在比较超微经皮肾镜取石术(PCNL)与置入支架的冲击波碎石术(SWL)治疗直径10 - 20毫米肾结石的效果、安全性及预后。
本研究在艾因夏姆斯大学医学院泌尿外科进行。符合纳入和排除标准后,90例患者通过封闭信封技术随机分为超微PCNL组或置入支架的SWL组,每组45例。术前、术后即刻以及术后2周和4周收集患者数据,评估手术时间、住院时间、并发症,包括血尿、发热、输血需求、残余结石及再次治疗需求。
超微PCNL组的结石清除率(SFR)高于置入支架的SWL组,差异无统计学意义(P值 = 0.316)。至于再次治疗需求,置入支架的SWL组略高于超微PCNL组,但差异无统计学意义(P值 = 0.681)。我们发现两组在术后并发症(分别为发热、血尿和输血需求)方面无统计学显著差异。超微PCNL组的手术时间和住院时间显著长于置入支架的SWL组,两者P值均< 0.001。
置入支架的SWL和超微PCNL都是治疗直径小于2厘米肾结石且并发症发生率低的良好选择。结石大小指数是再次治疗需求的重要预测因素。需要进一步研究比较两种干预措施基于结石大小的SFR。