Human Technopole, Viale Rita Levi-Montalcini 1, 20157 Milano, Italy.
Human Technopole, Viale Rita Levi-Montalcini 1, 20157 Milano, Italy; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden; Science for Life Laboratory, Solna, Sweden.
Mol Cell. 2024 Jan 4;84(1):12-13. doi: 10.1016/j.molcel.2023.12.001.
A recent publication in Nature by Arnould et al. describes a novel chromatin compartment, termed "damaged" or "D compartment," that facilitates the repair of DNA double-strand breaks but also increases the risk of potentially oncogenic translocation formation.
最近，Arnould 等人在《自然》杂志上发表的一篇文章描述了一种新型染色质隔室，称为“损伤”或“D 隔室”，它有助于修复 DNA 双链断裂，但也增加了潜在致癌易位形成的风险。
